Association of physical activity with neurofilament light chain trajectories in autosomal dominant frontotemporal lobar degeneration variant carriers

KB Casaletto, J Kornack, EW Paolillo, JC Rojas… - JAMA …, 2023 - jamanetwork.com
Importance Physical activity is associated with cognitive health, even in autosomal dominant
forms of dementia. Higher physical activity is associated with slowed cognitive and …

[HTML][HTML] Plasma lysosphingolipids in GRN-related diseases: Monitoring lysosomal dysfunction to track disease progression

W Khrouf, D Saracino, B Rucheton, M Houot… - Neurobiology of …, 2023 - Elsevier
GRN mutations are among the main genetic causes of frontotemporal dementia (FTD).
Considering the progranulin involvement in lysosomal homeostasis, we aimed to evaluate if …

Feasibility and acceptability of remote smartphone cognitive testing in frontotemporal dementia research

JC Taylor, HW Heuer, AL Clark, AB Wise… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction Remote smartphone assessments of cognition, speech/language, and motor
functioning in frontotemporal dementia (FTD) could enable decentralized clinical trials and …

The temporal event-based model: Learning event timelines in progressive diseases

PA Wijeratne, A Eshaghi, WJ Scotton, M Kohli… - Imaging …, 2023 - direct.mit.edu
Timelines of events, such as symptom appearance or a change in biomarker value, provide
powerful signatures that characterise progressive diseases. Understanding and predicting …

Reliability and Validity of Smartphone Cognitive Testing for Frontotemporal Lobar Degeneration

AM Staffaroni, AL Clark, JC Taylor, HW Heuer… - JAMA Network …, 2024 - jamanetwork.com
Importance Frontotemporal lobar degeneration (FTLD) is relatively rare, behavioral and
motor symptoms increase travel burden, and standard neuropsychological tests are not …

Weight Change and Neuropsychiatric Symptoms in Alzheimer's Disease and Frontotemporal Dementia: Associations with Cognitive Decline

CB Morrow, J Leoutsakos, H Yan… - Journal of …, 2023 - content.iospress.com
Weight changes, neuropsychiatric symptoms (NPS), and cognitive decline often coincide in
Alzheimer's disease (AD) and frontotemporal dementia (FTD); however, the direction of their …