Tyrosine kinases have been intensively investigated as drug targets for several decades,
since they regulate many cellular processes including cell growth, differentiation, and …

With the recent success in calculating protein structures from amino acid sequences using
artificial intelligence-based algorithms, an important next step is to decipher how dynamics …

The fluorine-19 nucleus was recognized early to harbor exceptional properties for NMR
spectroscopy. With 100% natural abundance, a high gyromagnetic ratio (83% sensitivity …

A review of the literature published from January to December 2019 on theoretical aspects
of nuclear magnetic shielding is presented. It covers both non-relativistic and relativistic …

Nuclear magnetic resonance (NMR) spectroscopy has contributed to structure-based drug
development (SBDD) in a unique way compared to the other biophysical methods. The …

A primary biological function of multi-spanning membrane proteins is to transfer information
and/or materials through a membrane by changing their conformations. Therefore, particular …

A review of key publications from 2020, describing methodological developments and
research applications of NMR of proteins and nucleic acids. Particularly novel approaches …

The unique strength of solution-state nuclear magnetic resonance (NMR) is to contribute not
only to determine high-resolution structures of macromolecules but also to provide …

Asia-Pacific NMR (APNMR) has been an important scientific event in the region, engaging a
large number of NMR scientists from academia and industries. The 8th APNMR symposium …

The enzymes of the Claisen-condensing family catalyse the condensation reaction between
acetyl coenzyme A (AcCoA) and an α-ketoacid. The well-characterised members of this …