Cancer is a major threat to human health. Diagnosis and treatment using precision medicine
is expected to be an effective method for preventing the initiation and progression of cancer …

We have witnessed rapid development of fluorescence molecular imaging of solid tumors for
cancer diagnosis and image-guided surgery in the past decade. Many biomarkers unique to …

Purpose: Positive margins dominate clinical outcomes after surgical resections in most solid
cancer types, including head and neck squamous cell carcinoma. Unfortunately, surgeons …

For many solid tumors, surgical resection remains the gold standard and tumor-involved
margins are associated with poor clinical outcomes. Near-infrared (NIR) fluorescence …

Optical image-guided cancer surgery is a promising technique to adequately determine
tumor margins by tumor-specific targeting, potentially resulting in complete resection of …

Oral cancer, as one of the most prevalent and invasive cancers that invade local tissue, can
cause metastasis, and have high mortality. In 2018, around 355,000 worldwide oral cancers …

Results: Both fluorescently labeled antibodies had similar pharmacodynamic properties and
minimal toxicities. Two infusion reactions occurred with cetuximab and none with …

Near-infrared fluorescence (NIRF) molecular imaging holds great promise as a new “point-of-
care” medical imaging modality that can potentially provide the sensitivity of nuclear …

In the past several decades, a number of novel fluorescence image-guided surgery (FGS)
contrast agents have been under development, with many in clinical translation and …

Molecular image-guided surgery has the potential for translating the tools of molecular
pathology to real-time guidance in surgery. As a whole, there are incredibly positive …