Synthesis and applications of sodium sulfinates (RSO 2 Na): a powerful building block for the synthesis of organosulfur compounds

RJ Reddy, AH Kumari - RSC advances, 2021 - pubs.rsc.org
This review highlights the preparation of sodium sulfinates (RSO2Na) and their multifaceted
synthetic applications. Substantial progress has been made over the last decade in the …

Multicomponent Reactions (MCRs) with o‐Quinone Methides

MTM Martins, FRF Dias, RSM de Moraes… - The Chemical …, 2022 - Wiley Online Library
This article presents a comprehensive overview of multicomponent reactions (MCRs) that
proceed via ortho‐quinone methide intermediates (o‐QM) generated in the reaction …

Au (PPh3) Cl/AgOTf/TsOH-Catalyzed Cascade Reaction between 1-(2-Hydroxyphenyl)-propargyl Alcohols and β-Oxoketones (Amides, Acid): Diastereoselective …

Y Zhang, G Deng - The Journal of Organic Chemistry, 2024 - ACS Publications
In the Au (PPh3) Cl/AgOTf/TsOH/MeCN/N2/25° C system, diastereoselective synthesis of cis-
3a, 8a-dihydrofuro [2, 3-b] benzofuran derivatives with a substituent at the 8a-position has …

Copper-Catalyzed Cascade Annulation of o-Hydroxyphenyl Propargylamines with Pyrazolin-5-ones to Access Pyrano[2,3-c]pyrazoles

MH Yi, HS Jin, RB Wang, LM Zhao - The Journal of Organic …, 2022 - ACS Publications
An efficient copper-catalyzed cascade annulation of o-hydroxyphenyl propargylamines and
pyrazolin-5-ones is described. This methodology leads to the rapid assembly of a series of …

Tandem Cyclization of o-Hydroxyphenyl Propargyl Alcohols with Thionucleophiles: A Metal-Free and Modular Access to 3-Fluoroalkylsulfonyl/Thio Benzofurans

L Wang, L Bao, G Li, J Dong, X Xu - The Journal of Organic …, 2024 - ACS Publications
Despite both fluoroalkylsulfonyl groups and benzofurans are important bioactive moieties,
the construction of fluoroalkanesulfonylated benzofurans that incorporate these two …

Relay Cu(I)/Brønsted Base Catalysis for Phospha‐Michael Addition/5‐exodig Cyclization/Isomerization of insitu Formed aza‐Alkynyl o‐quinone methides …

L Chen, XY Liu, J Zhang, L Duan… - Advanced Synthesis & …, 2021 - Wiley Online Library
Abstract A relay Cu (I)/Brønsted base catalyzed one‐pot phospha‐Michael addition/5‐exo‐
dig cyclization/isomerization of in situ generated aza‐alkynyl o‐quinone methides (N‐o …

Regioselective Reversal in One-Pot and Two-Step Reaction of 1-(2-Hydroxyphenyl)-Propargyl Alcohols with Aryl/Alkyl Mercaptan: Construction of 3-(Alkylthio) …

Y Zhu, G Deng - The Journal of Organic Chemistry, 2024 - ACS Publications
The Cu (MeCN) 4PF6-catalyzed reaction of 1-(2-hydroxyphenyl)-propargyl alcohols with
aryl/alkyl mercaptan and subsequent treatment with K2CO3 only offered 3-(alkylthio) …

Metal‐Free Cascade 1, 4‐Conjugate Addition/Selective Annulation Strategy for Divergent Synthesis of Polysubstituted Imidazoles and 4‐Alkenylquinazolines

Q Tang, K Xu, X He, Y Shang - Advanced Synthesis & Catalysis, 2022 - Wiley Online Library
A metal‐free cascade annulation of propagylamines with amidines for divergent synthesis of
polysubstituted imidazoles and 4‐alkenylquinazolines has been developed. The reaction is …

Five-membered ring systems: furans and benzofurans

H Kwiecień, A Wodnicka - Progress in Heterocyclic Chemistry, 2020 - Elsevier
Furans and their benzo-fused derivatives possess a diverse set of properties that allow a
wide range of applications, spanning from medicinal chemistry to photo-and …

Lewis acid-catalyzed tandem cyclization of in situ generated o-quinone methides and arylsulfonyl hydrazides for a one-pot entry to 3-sulfonylbenzofurans

FX Meng, RN Wang, HL Huang, SW Gong… - Organic Chemistry …, 2019 - pubs.rsc.org
A Lewis acid-catalyzed one-pot aza-Michael addition/fragmentation/sulfinyl conjugate
addition/cyclization cascade of o-QMs and arylsulfonyl hydrazides is described for the first …