[HTML][HTML] Prevention of atherothrombotic events in patients with diabetes mellitus: from antithrombotic therapies to new-generation glucose-lowering drugs

G Patti, I Cavallari, F Andreotti, P Calabro… - Nature Reviews …, 2019 - nature.com
Diabetes mellitus is an important risk factor for a first cardiovascular event and for worse
outcomes after a cardiovascular event has occurred. This situation might be caused, at least …

Antithrombotic therapy for atherosclerotic cardiovascular disease risk mitigation in patients with coronary artery disease and diabetes mellitus

D Capodanno, DJ Angiolillo - Circulation, 2020 - Am Heart Assoc
Patients with diabetes mellitus (DM) are characterized by enhanced thrombotic risk
attributed to multiple mechanisms including hyperreactive platelets, hypercoagulable status …

[PDF][PDF] Comparative Effectiveness of Aspirin Dosing in Cardiovascular Disease and Diabetes Mellitus: A Subgroup Analysis of the ADAPTABLE Trial

DI Narcisse, H Kim, LM Wruck, AL Stebbins… - Diabetes …, 2024 - Am Diabetes Assoc
OBJECTIVE Patients with diabetes mellitus (DM) and concomitant atherosclerotic
cardiovascular disease (ASCVD) must be on the most effective dose of aspirin to mitigate …

[HTML][HTML] Diabetes and antiplatelet therapy: from bench to bedside

JRR Rios, F Franchi, F Rollini… - … diagnosis and therapy, 2018 - ncbi.nlm.nih.gov
Diabetes mellitus (DM) is a metabolic disorder associated with accelerated atherogenesis
and an increased risk of atherothrombotic complications. Multiple mechanisms contribute to …

[HTML][HTML] Precision antiplatelet therapy

B Rocca, C Patrono - Research and Practice in Thrombosis and …, 2023 - Elsevier
A State of the Art lecture titled “Personalizing Antiplatelet Therapy Based on Platelet
Turnover and Metabolic Phenotype” was presented by Bianca Rocca at the International …

[HTML][HTML] Effects of vorapaxar on clot characteristics, coagulation, inflammation, and platelet and endothelial function in patients treated with mono‐and dual …

K Bliden, R Chaudhary, A Kuliopulos, H Tran… - Journal of Thrombosis …, 2020 - Elsevier
Background Vorapaxar is indicated with standard antiplatelet therapy (APT) in patients with
a history of myocardial infarction (MI) or peripheral arterial disease (PAD). Objectives To …

Is arachidonic acid stimulation really a test for the response to aspirin? Time to think again?

B Olechowski, A Ashby, M Mariathas… - Expert review of …, 2017 - Taylor & Francis
Introduction: Platelets play a key role in pathogenesis of atherothrombosis. Activated
platelets initiate thrombus formation. Antiplatelet therapy (APT) modifies these properties …

[HTML][HTML] Aspirin for primary cardiovascular prevention in patients with diabetes: uncertainties and opportunities

M Del Bianco-Rondeau… - Thrombosis and …, 2022 - thieme-connect.com
The use of the antiplatelet agent aspirin (acetylsalicylic acid) was previously routinely
recommended for the primary prevention of cardiovascular (CV) events in patients with …

Appraising the contemporary role of aspirin for primary and secondary prevention of atherosclerotic cardiovascular events

D Calderone, S Ingala, MS Mauro… - Expert Review of …, 2021 - Taylor & Francis
Introduction Although the role of aspirin for primary prevention of atherosclerotic
cardiovascular disease (ASCVD) has been disputed, its use in secondary ASCVD …

Effect of different doses of acetylsalicylic acid on the antithrombotic activity of clopidogrel in a mouse arterial thrombosis model

R Ni, N Vaezzadeh, J Zhou, JI Weitz… - … , and vascular biology, 2018 - Am Heart Assoc
Objective—Dual-antiplatelet therapy with acetylsalicylic acid and a P2Y12 antagonist, such
as clopidogrel, is the standard of care for acute coronary syndromes. However, the drugs …