Cell-cell fusion between eukaryotic cells is a general process involved in many
physiological and pathological conditions, including infections by bacteria, parasites, and …

The past few years have brought substantial progress toward understanding how human
cytomegalovirus (HCMV) enters the remarkably wide spectrum of cell types and tissues that …

Human cytomegalovirus (HCMV) is the most common congenital infection and a leading
cause of stillbirth, neurodevelopmental impairment, and pediatric hearing loss worldwide …

Human cytomegalovirus (HCMV) can cause severe diseases in fetuses, newborns, and
immunocompromised individuals. Currently, no vaccines are approved, and treatment …

Human CMV (HCMV) exhibits a broad cell tropism that depends on two virion glycoprotein
complexes: a trimeric complex (gH/gL/gO) that facilitates viral infection primarily in …

Human cytomegalovirus (HCMV) is an important pathogen in transplant patients and in
congenital infection. Previously, we demonstrated that vaccination with a recombinant viral …

Human cytomegalovirus (HCMV) encodes multiple surface glycoprotein complexes to infect
a variety of cell types. The HCMV Pentamer, composed of gH, gL, UL128, UL130, and …

Vaccination against human cytomegalovirus (CMV) infection remains high priority. A
recombinant form of a protein essential for CMV entry, glycoprotein B (gB), demonstrated …

Herpesvirus infections are a leading cause of neurodevelopmental delay in newborns and
end-organ disease in immunocompromised patients. One leading strategy to reduce the …

CD58 is an adhesion molecule that is known to play a critical role in costimulation of effector
cells and is intrinsic to immune synapse structure. Herein, we describe a virally encoded …