Diabetes mellitus (DM) is one of the most debilitating chronic diseases worldwide, with
increased prevalence and incidence. In addition to its macrovascular damage, through its …

Neurodegenerative diseases (NDDs) and cardiovascular diseases (CVDs) are illnesses that
affect the nervous system and heart, all of which are vital to the human body. To maintain …

So far, the search for a cure for Alzheimer Disease (AD) has been unsuccessful. The only
approved drugs attenuate some symptoms, but do not halt the progress of this disease …

The immune system protects the body from infectious agents such as bacteria, viruses, or
fungi. Once encountered with pathogens or antigens, the innate and adaptive arms of the …

Oxidative stress is a state of imbalance between oxidation and antioxidation. Excessive ROS
levels are an important factor in tumor development. Damage stimulation and excessive …

Background Nuclear factor erythroid 2-related factor 2 (Nrf2) is a classical nuclear
transcription factor that regulates the system's anti-oxidative stress response. The activation …

Glucosinolates (GSLs), found mainly in species of the Brassicaceae family, are one of the
most well-studied classes of secondary metabolites. Produced by the action of myrosinase …

Dysregulation of innate immune responses can result in chronic inflammatory conditions.
Glucocorticoids, the current frontline therapy, are effective immunosuppressive drugs but …

Fragile X (FMR1) premutation is a common mutation that affects about 1 in 200 females and
1 in 450 males and can lead to the development of fragile-X-associated tremor/ataxia …

Myrosinase is a biotechnological tool for the preparation of sulforaphane and sulforaphene
with a variety of excellent biological activities. In this study, a gene encoding the novel …