Application of artificial intelligence and machine learning for COVID-19 drug discovery and vaccine design

H Lv, L Shi, JW Berkenpas, FY Dao… - Briefings in …, 2021 - academic.oup.com
The global pandemic of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2, has led to a dramatic loss of human life worldwide …

Application of multilayer network models in bioinformatics

Y Lv, S Huang, T Zhang, B Gao - Frontiers in Genetics, 2021 - frontiersin.org
Multilayer networks provide an efficient tool for studying complex systems, and with current,
dramatic development of bioinformatics tools and accumulation of data, researchers have …

[HTML][HTML] Identification of cyclin protein using gradient boost decision tree algorithm

H Zulfiqar, SS Yuan, QL Huang, ZJ Sun, FY Dao… - Computational and …, 2021 - Elsevier
Cyclin proteins are capable to regulate the cell cycle by forming a complex with cyclin-
dependent kinases to activate cell cycle. Correct recognition of cyclin proteins could provide …

Deep-4mCW2V: A sequence-based predictor to identify N4-methylcytosine sites in Escherichia coli

H Zulfiqar, ZJ Sun, QL Huang, SS Yuan, H Lv, FY Dao… - Methods, 2022 - Elsevier
Abstract N4-methylcytosine (4mC) is a type of DNA modification which could regulate
several biological progressions such as transcription regulation, replication and gene …

iTTCA-RF: a random forest predictor for tumor T cell antigens

S Jiao, Q Zou, H Guo, L Shi - Journal of translational medicine, 2021 - Springer
Background Cancer is one of the most serious diseases threatening human health. Cancer
immunotherapy represents the most promising treatment strategy due to its high efficacy and …

Deep-4mCGP: A Deep Learning Approach to Predict 4mC Sites in Geobacter pickeringii by Using Correlation-Based Feature Selection Technique

H Zulfiqar, QL Huang, H Lv, ZJ Sun, FY Dao… - International Journal of …, 2022 - mdpi.com
4mC is a type of DNA alteration that has the ability to synchronize multiple biological
movements, for example, DNA replication, gene expressions, and transcriptional …

Potential antiviral activities of chrysin against hepatitis B virus

SA Bhat, SK Hasan, ZA Parray, ZI Siddiqui, S Ansari… - Gut Pathogens, 2023 - Springer
Background Interferon and nucleos (t) ide analogues are current therapeutic treatments for
chronic Hepatitis B virus (HBV) infection with the limitations of a functional cure. Chrysin (5, 7 …

Current status and future prospects of drug–target interaction prediction

X Ru, X Ye, T Sakurai, Q Zou, L Xu… - Briefings in Functional …, 2021 - academic.oup.com
Drug–target interaction prediction is important for drug development and drug repurposing.
Many computational methods have been proposed for drug–target interaction prediction due …

[HTML][HTML] Empirical comparison and recent advances of computational prediction of hormone binding proteins using machine learning methods

H Zulfiqar, Z Guo, BK Grace-Mercure, ZY Zhang… - Computational and …, 2023 - Elsevier
Hormone binding proteins (HBPs) belong to the group of soluble carrier proteins. These
proteins selectively and non-covalently interact with hormones and promote growth …

[PDF][PDF] Computational identification of N4-methylcytosine sites in the mouse genome with machine-learning method

H Zulfiqar, RS Khan, F Hassan, K Hippe… - Math. Biosci …, 2021 - pdfs.semanticscholar.org
N4-methylcytosine (4mC) is a kind of DNA modification which could regulate multiple
biological processes. Correctly identifying 4mC sites in genomic sequences can provide …