[HTML][HTML] The role of arylamine N-acetyltransferases in chronic degenerative diseases: Their possible function in the immune system
O Hernandez-Gonzalez, DJ Herrera-Vargas… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Since their discovery, arylamine N-acetyltransferases 1 and 2 (NAT1 and NAT2,
respectively) have been associated with the metabolism of xenobiotics. NAT2 is the main …
respectively) have been associated with the metabolism of xenobiotics. NAT2 is the main …
Association between N-acetyltransferase 2 polymorphism and bladder cancer risk: results from studies of the past decade and a meta-analysis
H Wu, X Wang, L Zhang, N Mo, Z Lv - Clinical genitourinary cancer, 2016 - Elsevier
Numerous studies have identified that the slow acetylation status of N-acetyltransferase 2
(NAT2) is associated with an elevated bladder cancer risk. However, the results remain …
(NAT2) is associated with an elevated bladder cancer risk. However, the results remain …
Genotype-environment interaction analysis of NQO1, CYP2E1, and NAT2 polymorphisms and the risk of childhood acute lymphoblastic leukemia: a report from the …
A Medina-Sanson, JC Núñez-Enríquez… - Frontiers in …, 2020 - frontiersin.org
Background: Acute lymphoblastic leukemia (ALL) is the main type of cancer in children. In
Mexico and other Hispanic populations, the incidence of this neoplasm is one of the highest …
Mexico and other Hispanic populations, the incidence of this neoplasm is one of the highest …
Altered Arylamine N-acetyltransferase 1 and miR-1290 Levels in Childhood Acute Lymphoblastic Leukemia: A Pilot Study
O Hernandez-Gonzalez, RDC Milan-Segovia… - in vivo, 2023 - iv.iiarjournals.org
Background/Aim: Arylamine N-acetyltransferase 1 and 2 (NAT1 and NAT2) are drug-
metabolizing enzymes that play a key role in the development of acute lymphoblastic …
metabolizing enzymes that play a key role in the development of acute lymphoblastic …
Effect of N-acetyltransferase 2 genetic polymorphism on 4,4′-methylenebis(2-chloroaniline)-induced genotoxicity and oxidative stress
MR Habil, RA Salazar-González, MA Doll… - Archives of toxicology, 2023 - Springer
Methylenebis (2-chloroaniline) or MOCA is an aromatic amine used primarily in
polyurethane and rubber industry. MOCA has been linked to hepatomas in animal studies …
polyurethane and rubber industry. MOCA has been linked to hepatomas in animal studies …
The effect of the rs1799931 G857A (G286E) polymorphism on N-acetyltransferase 2-mediated carcinogen metabolism and genotoxicity differs with heterocyclic …
DW Hein, RA Salazar-González, MA Doll, Y Zang - Archives of Toxicology, 2023 - Springer
Abstract Human N-acetyltransferase 2 (NAT2) is subject to genetic polymorphism in human
populations. In addition to the reference NAT2* 4 allele, two genetic variant alleles (NAT2 …
populations. In addition to the reference NAT2* 4 allele, two genetic variant alleles (NAT2 …
Associations of interleukin-10 gene polymorphisms with acute myeloid leukemia in human (Egypt)
R Rashed, RE Shafik, NF Shafik… - Journal of Cancer …, 2018 - journals.lww.com
Background: Acute myeloid leukemia (AML) is a cytogenetically and molecularly
heterogeneous diseases, and characterization of transforming genetic events is becoming …
heterogeneous diseases, and characterization of transforming genetic events is becoming …
A case-control study in NAT2 gene polymorphism studies in patients diagnosed with acute myeloid leukemia
A Farasani - Acta Biochimica Polonica, 2023 - abp.ptbioch.edu.pl
Introduction: Acute myeloid leukemia (AML) is a clinically defined heterogeneous disease
whose pathophysiology is currently unknown. The association of NAT2 acetylation profiles …
whose pathophysiology is currently unknown. The association of NAT2 acetylation profiles …
Genetic polymorphisms of arylamine N-acetyltransferases 1 and 2 and the likelihood of developing pediatric acute lymphoblastic leukemia
O Hernández-González, JJ Ortiz-Zamudio… - Leukemia & …, 2018 - Taylor & Francis
Acute lymphoblastic leukemia (ALL) is one of the main causes of death in children and is
associated with both genetic susceptibility and environmental factors. Genes encoding the …
associated with both genetic susceptibility and environmental factors. Genes encoding the …
Association between NAT2 polymorphisms and acute leukemia risk: A meta-analysis
X Zhu, Y Liu, G Chen, Q Guo, Z Zhang, L Zhao, R Wei… - Medicine, 2019 - journals.lww.com
Background: N-acetyl-transferase 2 (NAT2) polymorphisms have been demonstrated to be
associated with acute leukemia (AL); however, the results remain controversial. The present …
associated with acute leukemia (AL); however, the results remain controversial. The present …