NLRP3 is an intracellular sensor protein that when activated by a broad spectrum of
exogenous and endogenous stimuli leads to inflammasome formation and pyroptosis,. The …

Auxins are hormones that have central roles and control nearly all aspects of growth and
development in plants,–. The proteins in the PIN-FORMED (PIN) family (also known as the …

Integrator and protein phosphatase 2A (PP2A) form a complex that dephosphorylates
paused RNA polymerase II (Pol II), cleaves the nascent RNA, and terminates transcription …

Over the past decade, technical and methodological improvements in cryogenic electron
microscopy (cryo-EM) single-particle analysis have enabled routine high-resolution …

Cysteine plays an essential role in cellular redox homoeostasis as a key constituent of the
tripeptide glutathione (GSH). A rate limiting step in cellular GSH synthesis is the availability …

Complex I is the first enzyme in the respiratory chain, which is responsible for energy
production in mitochondria and bacteria. Complex I couples the transfer of two electrons …

CRISPR-Cas systems have been co-opted by Tn7-like transposable elements to direct RNA-
guided transposition. Type VK CRISPR-associated transposons rely on the concerted …

The power of computer simulations, including machine‐learning, has become an
inseparable part of scientific analysis of biological data. This has significantly impacted the …

Mediator is a conserved coactivator complex that enables the regulated initiation of
transcription at eukaryotic genes,–. Mediator is recruited by transcriptional activators and …

Canonical CRISPR–Cas systems provide adaptive immunity against mobile genetic
elements. However, type IF, IB and VK systems have been adopted by Tn7-like transposons …