The major constituent of the outer membrane of Gram-negative bacteria is
lipopolysaccharide (LPS), which is comprised of lipid A, core oligosaccharide, and O …

Through their specific interactions with proteins, cellular glycans play key roles in a wide
range of physiological and pathological processes. One of the main goals of research in the …

Introduction: Over the last decades, glycoconjugate vaccines have been proven to be a
successful strategy to prevent infectious diseases. Many diseases remain to be controlled …

Lectin receptor-like kinases (LecRLKs), a plant-specific receptor-like kinase (RLK) sub-
family, have been recently found to play crucial roles in plant development and responses to …

Antigen-presenting cells (APCs) are present throughout the human body—in tissues, at
barrier sites and in the circulation. They are critical for processing external signals to instruct …

Highlights•A brief overview of CBD development in recent decades is presented.•
Approaches for accessing specific carbohydrates and glycoconjugates are …

Glycans are expressed on the surface of nearly all host and bacterial cells. Not surprisingly,
glycan-mediated molecular interactions play a vital role in bacterial pathogenesis and host …

Glycans and glycan binding proteins (GBPs or lectins) are essential components in almost
every aspect of immunology. Investigations of the interactions between glycans and GBPs …

The dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-
SIGN) is an innate immune C-type lectin receptor that recognizes carbohydrate-based …

The relevance of protein-glycan interactions in immunity has long been underestimated. Yet,
the immune system possesses numerous classes of glycan-binding proteins, so-called …