Translational pain assessment: could natural animal models be the missing link?

MP Klinck, JS Mogil, M Moreau, BDX Lascelles… - Pain, 2017 - journals.lww.com
Failure of analgesic drugs in clinical development is common. Along with the current
“reproducibility crisis” in pain research, this has led some to question the use of animal …

Feline chronic pain and osteoarthritis

BP Monteiro - Veterinary Clinics: Small Animal Practice, 2020 - vetsmall.theclinics.com
Pain is a personal, complex, and multidimensional experience involving sensory and
emotional components. The intensity of pain does not correlate linearly with the severity of …

[HTML][HTML] Characterization of osteoarthritis in cats and meloxicam efficacy using objective chronic pain evaluation tools

M Guillot, M Moreau, M Heit, J Martel-Pelletier… - The Veterinary …, 2013 - Elsevier
This study aimed to characterize osteoarthritis (OA)-related chronic pain and disability in
experimental cats with naturally occurring OA. Peak vertical ground reaction force (PVF) …

Caregiver placebo effect in analgesic clinical trials for cats with naturally occurring degenerative joint disease‐associated pain

ME Gruen, DC Dorman, BDX Lascelles - Veterinary Record, 2017 - Wiley Online Library
A literature review identified six placebo‐controlled studies of analgesics in client‐owned
cats with degenerative joint disease‐associated pain. Five studies with 96 cats had …

Feline musculoskeletal pain index: responsiveness and testing of criterion validity

J Benito, B Hansen, V Depuy… - Journal of Veterinary …, 2013 - Wiley Online Library
Background Progress in establishing if therapies provide relief to cats with degenerative
joint disease (DJD)‐associated pain is hampered by a lack of validated owner‐administered …

Criterion validation testing of clinical metrology instruments for measuring degenerative joint disease associated mobility impairment in cats

ME Gruen, EH Griffith, AE Thomson, W Simpson… - PLoS …, 2015 - journals.plos.org
Introduction Degenerative joint disease and associated pain are common in cats,
particularly in older cats. There is a need for treatment options, however evaluation of …

Analgesic efficacy of tramadol in cats with naturally occurring osteoarthritis

BP Monteiro, MP Klinck, M Moreau, M Guillot… - PLoS …, 2017 - journals.plos.org
Objectives This study aimed to (1) compare outcome assessments in normal and
osteoarthritic cats and (2) evaluate the analgesic efficacy of tramadol in feline osteoarthritis …

Robenacoxib shows efficacy for the treatment of chronic degenerative joint disease-associated pain in cats: a randomized and blinded pilot clinical trial

D Adrian, JN King, RS Parrish, SB King… - Scientific Reports, 2021 - nature.com
The main objective of this pilot clinical trial was to evaluate outcome measures for the
assessment of the nonsteroidal anti-inflammatory drug (NSAID) robenacoxib in cats with …

Analgesic efficacy of an oral transmucosal spray formulation of meloxicam alone or in combination with tramadol in cats with naturally occurring osteoarthritis

BP Monteiro, MP Klinck, M Moreau, M Guillot… - Veterinary anaesthesia …, 2016 - Elsevier
Objective To evaluate the analgesic efficacy of meloxicam oral transmucosal spray (OTMS)
alone and with tramadol in cats with osteoarthritis (OA). Study design Randomized, blinded …

Forelimb and hindlimb ground reaction forces of walking cats: assessment and comparison with walking dogs

RJ Corbee, H Maas, A Doornenbal… - The Veterinary …, 2014 - Elsevier
The primary aim of this study was to assess the potential of force plate analysis for
describing the stride cycle of the cat. The secondary aim was to define differences in feline …