According to the WHO, cancer caused almost 10 million deaths worldwide in 2020, ie,
almost one in six deaths. Among the most common are breast, lung, colon and rectal and …

Cancer is a class of diseases characterized by out-of-control cell growth (tumors); over 100
different types of cancer are known and classified by the type of cell that is initially affected …

A series of styrylquinolines was designed and synthesized based on the four main quinoline
scaffolds including oxine, chloroxine and quinolines substituted with a hydroxyl group or …

Simple, convenient, and green synthetic protocols have been developed for the one pot
synthesis of 2, 3-disubstituted quinazolin-4 (3H)-ones and 2-styryl-3-substituted quinazolin-4 …

Forty-eight analogues of CP-31398, an antitumor agent modulated the mutant p53 gene
were synthesized and their cytotoxicities against four cancer cell lines with different p-53 …

Iron chelators have emerged as a potential anti-cancer treatment strategy. In this study, a
series of novel thiosemicarbazone iron chelators containing a quinoline scaffold were …

A series of new unique acetylene derivatives of 8-hydroxy-and 8-methoxyquinoline-5-
sulfonamide 3a–f and 6a–f were prepared by reactions of 8-hydroxy-and 8 …

A group of styrylquinolines were synthesized and tested for their anti-proliferative activity.
Anti-proliferative activity was evaluated against the human colon carcinoma cell lines that …

Abstract Series of thirty‐two mono‐, di‐and tri‐substituted 8‐hydroxyquinoline‐2‐
carboxanilides were prepared by microwave‐assisted synthesis. The compounds were …

Four series of primaquine (PQ) derivatives were screened for antitubercular and
antiplasmodial activity: amides 1a-k, ureas 2a-s, semicarbazides 3a-c and bis-ureas 4a-u …