High grade B-cell lymphoma with rearrangements of MYC and BCL2 and/or BCL6: Double hit and triple hit lymphomas and double expressing lymphoma

A Rosenthal, A Younes - Blood reviews, 2017 - Elsevier
Diffuse large B-cell lymphomas with aberrations in MYC, BCL2 and/or BCL6 by genetic
alterations or protein expression represent a group of high grade B-cell lymphomas with …

Approach to the diagnosis and treatment of high-grade B-cell lymphomas with MYC and BCL2 and/or BCL6 rearrangements

P Sesques, NA Johnson - Blood, The Journal of the American …, 2017 - ashpublications.org
High-grade B-cell lymphomas (HGBLs) with MYC and BCL2 and/or BCL6 rearrangements,
so-called “double-hit” lymphomas (HGBL-DH), are aggressive lymphomas that form a …

Double-hit and double-protein-expression lymphomas: aggressive and refractory lymphomas

C Sarkozy, A Traverse-Glehen, B Coiffier - The Lancet Oncology, 2015 - thelancet.com
Double-hit lymphoma (DHL) is a subgroup of aggressive lymphomas with both MYC and
BCL2 gene rearrangements, characterised by a rapidly progressing clinical course that is …

How I treat double-hit lymphoma

JW Friedberg - Blood, The Journal of the American Society of …, 2017 - ashpublications.org
The 2016 revision of the World Health Organization (WHO) classification for lymphoma has
included a new category of lymphoma, separate from diffuse large B-cell lymphoma, termed …

Diffuse large B-cell lymphoma version 1.2016

AD Zelenetz, LI Gordon, WG Wierda… - Journal of the National …, 2016 - jnccn.org
Diffuse large B-cell lymphomas (DLBCL) are now considered a heterogeneous group of
distinct molecular subtypes (germinal center B-cell DLBCL, activated B-cell DLBCL, and …

[HTML][HTML] Inferior survival in high-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements is not associated with MYC/IG gene rearrangements

ED McPhail, MJ Maurer, WR Macon, AL Feldman… - …, 2018 - ncbi.nlm.nih.gov
High-grade B-cell lymphomas with MYC and BCL2 and/or BCL6 rearrangements (double-
/triple-hit lymphoma) have an aggressive clinical course. We investigated the prognostic …

Clinical impact of the 2016 update to the WHO lymphoma classification

RC Lynch, D Gratzinger, RH Advani - Current treatment options in …, 2017 - Springer
Opinion statement The 2016 revision of the WHO classification of lymphoid neoplasms
includes new entities along with a clearer definition of provisional and definitive subtypes …

Advances in diagnosis and management of diffuse large B-cell lymphoma

F Cabanillas, B Shah - Clinical Lymphoma Myeloma and Leukemia, 2017 - Elsevier
The management of diffuse large B-cell lymphoma (DLBCL) has been gradually evolving
since the discovery of its 2 major forms, the germinal center B-like (GCB) and activated B …

Outcomes in patients with aggressive B‐cell non‐Hodgkin lymphoma after intensive frontline treatment failure

EC Ayers, S Li, LJ Medeiros, DA Bond, KJ Maddocks… - Cancer, 2020 - Wiley Online Library
Background Salvage immunochemotherapy followed by high‐dose chemotherapy and
autologous stem cell transplantation is the standard‐of‐care second‐line treatment for …

[HTML][HTML] Aggressive B-cell lymphomas—from morphology to molecular pathogenesis

BJ Chen, F Fend, E Campo… - Annals of …, 2019 - aol.amegroups.org
The 2016 revised World Health Organization (WHO) classification of lymphoid malignancies
recognizes several distinct entities within the group of diffuse large B-cell lymphoma …