Agarwood oil nanoemulsion counteracts LPS-induced inflammation and oxidative stress in RAW264. 7 mouse macrophages
Purpose Oxidative stress and inflammation are key pathophysiological features of chronic
respiratory diseases, including asthma and chronic obstructive pulmonary disease (COPD) …
respiratory diseases, including asthma and chronic obstructive pulmonary disease (COPD) …
Computational design of phosphatidylinositol 3-kinase inhibitors
One of the most sought-after therapeutic targets for treating human cancers is the
phosphoinositide 3-kinase; PI3k is an integral part of the PI3K/protein kinase B signaling …
phosphoinositide 3-kinase; PI3k is an integral part of the PI3K/protein kinase B signaling …
[HTML][HTML] Glycogen synthase kinase-3β inhibitors as a novel promising target in the treatment of cancer: medicinal chemistry perspective
D Karati, KK Shaoo, KR Mahadik, D Kumr - Results in Chemistry, 2022 - Elsevier
Glycogen synthase kinase-3 beta (GSK-3β) is a desired pharmacological target for cancer
treatment. Despite its role in the development of various cancers, any target directing GSK-3 …
treatment. Despite its role in the development of various cancers, any target directing GSK-3 …
Computational Design of Plant‐Based Antistress Agents Targeting Nociceptin Receptor
Stress is the body's reaction to the challenges it faces, and it produces a multitude of
chemical molecules known as stressors as a result of these reactions. It's also a …
chemical molecules known as stressors as a result of these reactions. It's also a …
In-Silico Design, Synthesis, and Pharmacological Evaluation of Oxadiazole-Based Selective Cyclo-oxygenase-2 Inhibitors
A series of oxadiazole-based five-membered heterocyclic derivatives was designed and
synthesized with the intent of exclusive cyclo-oxygenase-2 (COX-2) inhibition to acquire anti …
synthesized with the intent of exclusive cyclo-oxygenase-2 (COX-2) inhibition to acquire anti …
Mutated Shiitake extracts inhibit melanin-producing neural crest-derived cells in zebrafish embryo
The ability of natural extracts to inhibit melanocyte activity is of great interest to researchers.
This study evaluates and explores the ability of mutated Shiitake (A37) and wildtype Shiitake …
This study evaluates and explores the ability of mutated Shiitake (A37) and wildtype Shiitake …
IN SILICO STUDIES OF SOME NEWLY DESIGNED BENZIMIDAZOLETHIAZOLIDINONE BASED ANTAGONISTS OF HUMAN ESTROGEN RECEPTOR.
Breast cancer is globally associated with majority of the women. Indeed, high estrogen
levels are the most common subtype of breast cancer. Three different classes of estrogen …
levels are the most common subtype of breast cancer. Three different classes of estrogen …
Evaluation of Moringa Oleifera Leaf Extract for its In vitro Antibacterial Properties, Mechanism of Action, and In vivo Corneal Ulcer Healing Effects in Rabbits' Eyes
Background M. oleifera is the most adapted tree species in different medicinal eco-systems
and has resilience against climate changes. This multiple-use tree provides healthy foods …
and has resilience against climate changes. This multiple-use tree provides healthy foods …
Computational design and in vitro assay of lantadene-based novel inhibitors of NS3 protease of dengue virus
Dengue virus (DENV) infection is one of the diseases for which no drug is available for the
treatment. The DENV NS2B-NS3 protease is considered to be the prime target for anti …
treatment. The DENV NS2B-NS3 protease is considered to be the prime target for anti …
In-silico STUDIES OF UNIQUE SCHIFF BASE OF BENZIMIDAZOLE DERIVATIVES AS ANTICANCER AGENTS.
One of the most hazardous illnesses affecting peopleis breast cancer, but there is currently
no permanent treatment available. New drug therapies with better pharmacokinetic …
no permanent treatment available. New drug therapies with better pharmacokinetic …