Antibiotic resistance: a rundown of a global crisis

B Aslam, W Wang, MI Arshad, M Khurshid… - Infection and drug …, 2018 - Taylor & Francis
The advent of multidrug resistance among pathogenic bacteria is imperiling the worth of
antibiotics, which have previously transformed medical sciences. The crisis of antimicrobial …

[HTML][HTML] Therapeutic strategies against bacterial biofilms

Y Bi, G Xia, C Shi, J Wan, L Liu, Y Chen, Y Wu… - Fundamental …, 2021 - Elsevier
The emergence of multi-drug resistance makes bacterial infection a major threat to public
health and economy. The formation of bacterial biofilms is one of the main reasons of …

Antimicrobial peptides of the genus Bacillus: a new era for antibiotics

CD Sumi, BW Yang, IC Yeo… - Canadian journal of …, 2015 - cdnsciencepub.com
The rapid onset of resistance reduces the efficacy of most conventional antimicrobial drugs
and is a general cause of concern for human well-being. Thus, there is great demand for a …

Synthesis, self-assembly, and biomedical applications of antimicrobial peptide–polymer conjugates

H Sun, Y Hong, Y Xi, Y Zou, J Gao, J Du - Biomacromolecules, 2018 - ACS Publications
Antimicrobial peptides (AMPs) have been attracting much attention due to their excellent
antimicrobial efficiency and low rate in driving antimicrobial resistance (AMR), which has …

The roles of antimicrobial peptides in innate host defense

G Diamond, N Beckloff, A Weinberg… - Current …, 2009 - ingentaconnect.com
Antimicrobial peptides (AMPs) are multi-functional peptides whose fundamental biological
role in vivo has been proposed to be the elimination of pathogenic microorganisms …

Towards sequence‐controlled antimicrobial polymers: effect of polymer block order on antimicrobial activity

PR Judzewitsch, TK Nguyen… - Angewandte Chemie …, 2018 - Wiley Online Library
Synthetic polymers have shown promise in combating multidrug‐resistant bacteria.
However, the biological effects of sequence control in synthetic antimicrobial polymers are …

De novo design of antimicrobial polymers, foldamers, and small molecules: from discovery to practical applications

GN Tew, RW Scott, ML Klein… - Accounts of chemical …, 2010 - ACS Publications
Antimicrobial peptides (AMPs) provide protection against a variety of pathogenic bacteria
and are, therefore, an important part of the innate immune system. Over the past decade …

A host defense peptide mimetic, brilacidin, potentiates caspofungin antifungal activity against human pathogenic fungi

TF Dos Reis, PA De Castro, RW Bastos… - Nature …, 2023 - nature.com
Fungal infections cause more than 1.5 million deaths a year. Due to emerging antifungal
drug resistance, novel strategies are urgently needed to combat life-threatening fungal …

Cationic amphiphiles, a new generation of antimicrobials inspired by the natural antimicrobial peptide scaffold

B Findlay, GG Zhanel, F Schweizer - Antimicrobial agents and …, 2010 - Am Soc Microbiol
Naturally occurring cationic antimicrobial peptides (AMPs) and their mimics form a diverse
class of antibacterial agents currently validated in preclinical and clinical settings for the …

Effect of hydrophobic groups on antimicrobial and hemolytic activity: Developing a predictive tool for ternary antimicrobial polymers

PT Phuong, S Oliver, J He, EHH Wong… - …, 2020 - ACS Publications
Antimicrobial polymers have emerged as a potential solution to the growing problem of
antimicrobial resistance. Although several studies have examined the effects of various …