Autologous fibrin scaffolds: When platelet-and plasma-derived biomolecules meet fibrin

E Anitua, P Nurden, R Prado, AT Nurden, S Padilla - Biomaterials, 2019 - Elsevier
The healing of vascularized mammalian tissue injuries initiate with hemostasis and clotting
as part of biological defense system leading to the formation of a fibrin clot in which activated …

Platelet-rich plasma in orthopedic therapy: a comparative systematic review of clinical and experimental data in equine and human musculoskeletal lesions

PM Brossi, JJ Moreira, TSL Machado… - BMC veterinary …, 2015 - Springer
Background This systematic review aimed to present and critically appraise the available
information on the efficacy of platelet rich plasma (PRP) in equine and human orthopedic …

Platelet-rich plasma efficacy versus corticosteroid injection treatment for chronic severe plantar fasciitis

RR Monto - Foot & ankle international, 2014 - journals.sagepub.com
Background: Chronic plantar fasciitis is a common orthopedic condition that can prove
difficult to successfully treat. In this study, autologous platelet-rich plasma (PRP), a …

[HTML][HTML] Regeneration of the anterior cruciate ligament: Current strategies in tissue engineering

T Nau, A Teuschl - World journal of orthopedics, 2015 - ncbi.nlm.nih.gov
Recent advancements in the field of musculoskeletal tissue engineering have raised an
increasing interest in the regeneration of the anterior cruciate ligament (ACL). It is the aim of …

New and emerging strategies in platelet‐rich plasma application in musculoskeletal regenerative procedures: General overview on still open questions and outlook

F Salamanna, F Veronesi, M Maglio… - BioMed Research …, 2015 - Wiley Online Library
Despite its pervasive use, the clinical efficacy of platelet‐rich plasma (PRP) therapy and the
different mechanisms of action have yet to be established. This overview of the literature is …

Plasma rich in growth factors (PRGF) as a treatment for high ankle sprain in elite athletes: a randomized control trial

L Laver, MR Carmont, MO McConkey… - Knee Surgery, Sports …, 2015 - Springer
Purpose Syndesmotic sprains are uncommon injuries that require prolonged recovery. The
influence of ultrasound-guided injections of platelet-rich plasma (PRP) into the injured …

[HTML][HTML] Tendinopathies and platelet-rich plasma (PRP): from pre-clinical experiments to therapeutic use

JF Kaux, P Drion, JL Croisier… - Journal of stem cells & …, 2015 - ncbi.nlm.nih.gov
Objectives: The restorative properties of platelets, through the local release of growth factors,
are used in various medical areas. This article reviews fundamental and clinical research …

A single dose of platelet-rich plasma improves the organization and strength of a surgically repaired rotator cuff tendon in rats

O Dolkart, O Chechik, Y Zarfati, T Brosh… - Archives of orthopaedic …, 2014 - Springer
Introduction Rotator cuff tear (RCT) is a common cause of pain and disability among adults.
Platelet-rich plasma (PRP) is a fraction of whole blood containing concentrated growth …

A review on animal models and treatments for the reconstruction of Achilles and flexor tendons

M Bottagisio, AB Lovati - Journal of Materials Science: Materials in …, 2017 - Springer
Tendon is a connective tissue mainly composed of collagen fibers with peculiar mechanical
properties essential to functional movements. The increasing incidence of tendon traumatic …

Optimization of an Injectable Tendon Hydrogel: The Effects of Platelet-Rich Plasma and Adipose-Derived Stem Cells on Tendon Healing In Vivo

GJ Chiou, C Crowe, R McGoldrick, K Hui… - … Engineering Part A, 2015 - liebertpub.com
Introduction: Acute and chronic tendon injuries would benefit from stronger and more
expeditious healing. We hypothesize that supplementation of a biocompatible tendon …