In the cerebral cortex, GABAergic interneurons have evolved as a highly heterogeneous
collection of cell types that are characterized by their unique spatial and temporal …

Cortical interneurons are a diverse group of neurons that project locally and are crucial for
regulating information processing and flow throughout the cortex. Recent studies in mice …

Precise generation of excitatory neurons and inhibitory interneurons is crucial for proper
formation and function of neural circuits in the mammalian brain. Because of the size and …

Microglia, the brain-resident macrophages, exhibit highly dynamic functions in
neurodevelopment and neurodegeneration. Human microglia possess unique features as …

The functional organization of the hippocampus is distributed as a gradient along its
longitudinal axis that explains its differential interaction with diverse brain systems. We show …

In spite of the high metabolic cost of cellular production, the brain contains only a fraction of
the neurons generated during embryonic development. In the rodent cerebral cortex, a first …

The mammalian cerebral cortex represents one of the most recent and astonishing
inventions of nature, responsible of a large diversity of functions that range from sensory …

Understanding how neurons of the striatum are formed and integrate into complex synaptic
circuits is essential to provide insight into striatal function in health and disease. In this …

Mitochondrial activity differs markedly between organs, but it is not known how and when
this arises. Here we show that cell lineage-specific expression profiles involving essential …

Inhibitory interneurons make up around 10–20% of the total neuron population in the
cerebral cortex. A hallmark of inhibitory interneurons is their remarkable diversity in terms of …