Developing safe and effective delivery strategies for localizing messenger RNA (mRNA)
payloads to the spleen is an important goal in the field of genetic medicine. Accomplishing …

Immersion water sports involve long-term apneas; therefore, athletes must physiologically
adapt to maintain muscle oxygenation, despite not performing pulmonary ventilation. Breath …

Figure 1 Hypothesized relationship between tissue ADC and tissue T2 relaxation time in
vivo. Around the tissue T2 relaxation time of 34 ms (liver tissue at 3T) and 61 ms (spleen …

Abstract β-thalassemia is a genetic hemoglobin (Hb) disorder that affects millions of people
world-wide. It is characterized by ineffective erythropoiesis and anemia. The resultant …

Myelosuppression is a major adverse effect of chemotherapy. With the increasing number of
cancer patients worldwide, there is a growing interest in therapeutic approaches that reduce …

Miltefosine (MTS) is the only approved oral drug for treating leishmaniasis caused by
intracellular Leishmania parasites that localize in macrophages of the liver, spleen, skin …

The spleen has variations in its morphology and is considered to acquire a defined shape in
the third month of gestation. However, few studies have investigated spleen development …

Considering its hematological and immunological functions, spleen is a very important
organ. A change occurs in its size as the spleen performs these functions. This study aims to …

Rickettsia rickettsii, the etiological agent of Rocky Mountain spotted fever (RMSF), a life-
threatening tick-borne disease that affects humans and various animal species, has been …

Background During embryogenesis, the spleen undergoes intricate developmental
processes, originating from mesenchymal cells in the dorsal mesentery. An accessory …