Cyclic dipeptides, also know as diketopiperazines (DKP), the simplest cyclic forms of
peptides widespread in nature, are unsurpassed in their structural and bio-functional …

As their name indicates, freshwater fungi occur on submerged substrates in fresh water
habitats. This review brings together the chemical diversity and biological activity of 199 of …

Fungi are well-known for their abundant supply of metabolites with unrivaled structure and
promising bioactivities. Naphthalenones are among these fungal metabolites, that are …

Cyclodepsipeptides are a large family of peptide-related natural products consisting of
hydroxy and amino acids linked by amide and ester bonds. A number of cyclodepsipeptides …

Polymer-supported catalysts have emerged as one of the sustainable and cost-effective
alternatives in organic synthetic chemistry. We have developed the first polymer-supported …

A critical biological event that contributes to the appearance and progress of cancer and
diabetes is the reversible phosphorylation of proteins, a process controlled by protein …

The popularity of botanical and other purported medicinal natural products (NPs) continues
to grow, especially among patients with chronic illnesses and patients managed on complex …

Antimicrobial resistance is emerging as a global health challenge that requires immediate
and concerted attention. Accordingly, the WHO has issued alerts urging to continue …

Co-cultivation of isopod-associated fungi Herpotrichia sp. SF09 and Trametes versicolor
SF09A led to the reciprocal induction of thirteen new compounds (1–7 and 9–13) with …

Inducible nitric oxide synthase (iNOS) produces NO from l-arginine and plays critical roles in
inflammation and immune activation. Selective and potent iNOS inhibitors may be potentially …