Invasive fungal infections continue to appear in record numbers as the
immunocompromised population of the world increases, owing partially to the increased …

The need for new antifungal agents is undeniable. Current therapeutic choices for the
treatment of invasive fungal infections are limited to three classes of drugs. Most used …

Invasive fungal infections in humans are generally associated with high mortality, making
the choice of antifungal drug crucial for the outcome of the patient. The limited spectrum of …

Mechanical breathing motions have a fundamental function in lung development and
disease, but little is known about how they contribute to host innate immunity. Here we use a …

Elucidating the biology of yeast in its full complexity has major implications for science,
medicine and industry. One of the most critical processes determining yeast life and …

Diabetes is known to increase susceptibility to infections, partly due to impaired granulocyte
function and changes in the innate immunity. Here, we investigate the effect of diabetes, and …

Ou-gon, an extract from Scutellaria baicalensis Georgi root, has been shown to exhibit
pronounced antifungal activity. The present study aimed to identify antifungal components of …

Mycoses are accountable for millions of infections yearly worldwide. Invasive candidiasis is
the most usual, presenting a high morbidity and mortality. Candida albicans remains the …

Fungal keratitis (FK) accounts for approximately half of the microbial keratitis encountered in
low middle income countries (LMICs) and predominantly affect the working rural-poor. FK …

Antimicrobial peptides, in particular α-defensins expressed by Paneth cells, control
microbiota composition and play a key role in intestinal barrier function and homeostasis …