The introduction of super‐resolution fluorescence microscopy has allowed the visualization
of single proteins in their biological environment. Recently, these techniques have been …

G protein coupled receptors (GPCRs) represent the most important targets in modern
pharmacology because of the different functions they mediate, especially within brain and …

Microglia are key players in maintaining brain homeostasis and exhibit phenotypic
alterations in response to epileptic stimuli. However, it is still relatively unknown if these …

None of the current superresolution microscopy techniques can reliably image the changes
in endogenous protein nanoclustering dynamics associated with specific conformations in …

Mature B cells coexpress both IgM and IgD B-cell antigen receptor (BCR) classes, which are
organized on the cell surface in distinct protein islands. The specific role of the IgD–BCR is …

Previous work from us and others has suggested that cholesterol is an important lipid in the
context of the organization of the actin cytoskeleton. However, reorganization of the actin …

Chemokines promote the recruitment of leukocytes to sites of infection and inflammation by
activating conventional heterotrimeric guanine nucleotide–binding protein (G protein) …

Serotonin1A receptors are important neurotransmitter receptors in the G protein-coupled
receptor (GPCR) family and modulate a variety of neurological, behavioral, and cognitive …

Introduction: The need to improve drug research and development productivity continues to
drive innovation in pharmacological assays. Technologies that can leverage the advantages …

Expression of the membrane-bound form of the immunoglobulin (Ig) as part of the antigen
receptor is indispensable for both the development and the effector function of B cells …