Neuroprotective effects of fermented tea in MPTP-induced Parkinson's disease mouse model via MAPK signaling-mediated regulation of inflammation and antioxidant …

YR Lee, GH Moon, D Shim, JC Kim, KJ Lee… - Food Research …, 2023 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disorder that is characterized by
dopaminergic neuronal damage. In this study, three tea extracts from Hadong, Korea, were …

Parkinson's disease models and death signaling: what do we know until now?

LFAT Pedrão, POS Medeiros, EC Leandro… - Frontiers in …, 2024 - frontiersin.org
Parkinson's disease (PD) is the second neurodegenerative disorder most prevalent in the
world, characterized by the loss of dopaminergic neurons in the Substantia Nigra (SN). It is …

Peripheral MC1R Activation Modulates Immune Responses and is Neuroprotective in a Mouse Model of Parkinson's Disease

P Srivastava, S Nishiyama, F Zhou, SH Lin… - Journal of Neuroimmune …, 2023 - Springer
Abstract Background Melanocortin 1 receptor (MC1R) is a key pigmentation gene, and loss-
of-function of MC1R variants that produce red hair may be associated with Parkinson's …

The Protection of EGCG Against 6-OHDA-Induced Oxidative Damage by Regulating PPARγ and Nrf2/HO-1 Signaling

Q Xu, Y Chen, D Chen… - Nutrition and Metabolic …, 2024 - journals.sagepub.com
6-Hydroxydopamine (6-OHDA) is a classic neurotoxin that has been widely used in
Parkinson's disease research. 6-OHDA can increase intracellular reactive oxygen species …

Dexmedetomidine, an alpha-2 adrenoceptors agonist, provides a neuroprotective effect for dopaminergic neurons in the substantia nigra and attenuates glucose …

SA Farzam, S Darabi, H Haghdoost-Yazdi… - Neurological …, 2024 - Taylor & Francis
Introduction Studies have shown that dexmedetomidine (DEX, an a2-adrenoceptors agonist)
provides a neuroprotective effect and influences blood glucose levels. Here, we evaluated …