Background The most common type of monogenic diabetes is maturity-onset diabetes of the
young (MODY), a clinically and genetically heterogeneous group of endocrine disorders that …

In addition to the common types of diabetes mellitus, two major monogenic diabetes forms
exist. Maturity-onset diabetes of the young (MODY) represents a heterogenous group of …

Genome-wide association studies have identified 240 independent loci associated with type
2 diabetes (T2D) risk, but this knowledge has not advanced precision medicine. In contrast …

Aims GCK-MODY leads to mildly elevated blood glucose typically not requiring therapy. It
has been described in all ethnicities, but mainly in Caucasian Europeans. Here we describe …

Neonatal diabetes mellitus (NDM) is defined as the occurrence of severe hyperglycemia in
infants under 6 months old and may be permanent (PNDM) or transient (TNDM). When …

Abstract Aims/Introduction To investigate the clinical and genetic characteristics of Chinese
patients with a phenotype consistent with maturity‐onset diabetes of the young type 2 and …

MODY2 is caused by heterozygous inactivating mutations in the glucokinase (GCK) gene
that result in persistent, stable and mild fasting hyperglycaemia (5.6–8.0 mmol/L …

To verify the type of diabetes mellitus (DM) remains an extremely important problem in
endocrinology, as along with types 1 and 2 DM there are rarer hereditary types of DM …

Верификация типа сахарного диабета (СД) остается крайне важным вопросом в
эндокринологии, так как наряду с 1-м и 2-м типами СД существуют более редкие …

Abstract Aims/Introduction Mutations in the glucokinase gene (GCK) are a pathogenetic
cause of maturity‐onset diabetes of the young. Studies have found that female patients with …