Early childhood caries (ECC) is one of the most prevalent diseases in children worldwide.
ECC is driven by a dysbiotic state of oral microorganisms mainly caused by a sugar‐rich …

Human enamel once formed cannot be biologically repaired or replaced. Saliva has a
significant role in remineralization of dental enamel. It not only has a buffering capacity to …

This review focuses on recent discoveries and delves in detail about what is known about
each of the proteins (amelogenin, ameloblastin, and enamelin) and proteinases (matrix …

In vertebrates and invertebrates, biomineralization is controlled by the cell and the proteins
they produce. A large number of these proteins are intrinsically disordered, gaining some …

Amelogenesis imperfecta (AI) describes a heterogeneous group of inherited dental enamel
defects reflecting failure of normal amelogenesis. Ameloblastin (AMBN) is the second most …

The FAM20 family of secreted proteins consists of three members (FAM20A, FAM20B, and
FAM20C) recently linked to developmental disorders suggesting roles for FAM20 proteins in …

INTRODUCTION The absence of teeth or edentulism has evolved on multiple occasions
within vertebrates, including birds, turtles, and a few groups of mammals (anteaters, baleen …

Amelotin (AMTN) is a relatively recently discovered enamel protein that is predominantly
expressed by ameloblasts during the maturation stage of amelogenesis and is present at …

Introduction: Developmental defects of the enamel manifest before tooth eruption and
include amelogenesis imperfecta, a rare disease of underlying gene mutations, and molar …

Vertebrate mineralized tissues, ie, enamel, dentin, cementum, and bone, have unique
hierarchical structures and chemical compositions. Although these tissues are similarly …