Pneumococcal capsules and their types: past, present, and future
Streptococcus pneumoniae (the pneumococcus) is an important human pathogen. Its
virulence is largely due to its polysaccharide capsule, which shields it from the host immune …
virulence is largely due to its polysaccharide capsule, which shields it from the host immune …
The fundamental link between pneumococcal carriage and disease
B Simell, K Auranen, H Käyhty, D Goldblatt… - Expert review of …, 2012 - Taylor & Francis
Streptococcus pneumoniae (pneumococcus) is a major cause of worldwide mortality and
morbidity, and to a large extent is vaccine-preventable. Nasopharyngeal carriage of …
morbidity, and to a large extent is vaccine-preventable. Nasopharyngeal carriage of …
Causes of severe pneumonia requiring hospital admission in children without HIV infection from Africa and Asia: the PERCH multi-country case-control study
KL O'Brien, HC Baggett, WA Brooks, DR Feikin… - The Lancet, 2019 - thelancet.com
Background Pneumonia is the leading cause of death among children younger than 5 years.
In this study, we estimated causes of pneumonia in young African and Asian children, using …
In this study, we estimated causes of pneumonia in young African and Asian children, using …
[HTML][HTML] Standard method for detecting upper respiratory carriage of Streptococcus pneumoniae: updated recommendations from the World Health Organization …
Abstract In 2003 the World Health Organization (WHO) convened a working group and
published a set of standard methods for studies measuring nasopharyngeal carriage of …
published a set of standard methods for studies measuring nasopharyngeal carriage of …
Pneumococcal within-host diversity during colonization, transmission and treatment
Characterizing the genetic diversity of pathogens within the host promises to greatly improve
surveillance and reconstruction of transmission chains. For bacteria, it also informs our …
surveillance and reconstruction of transmission chains. For bacteria, it also informs our …
Effect of pneumococcal conjugate vaccination on serotype-specific carriage and invasive disease in England: a cross-sectional study
Background We investigated the effect of the 7-valent pneumococcal conjugate vaccine
(PCV7) programme in England on serotype-specific carriage and invasive disease to help …
(PCV7) programme in England on serotype-specific carriage and invasive disease to help …
[PDF][PDF] Clinical implications of pneumococcal serotypes: invasive disease potential, clinical presentations, and antibiotic resistance
JY Song, MH Nahm… - Journal of Korean medical …, 2013 - synapse.koreamed.org
Streptococcus pneumoniae can asymptomatically colonize the nasopharynx and cause a
diverse range of illnesses. This clinical spectrum from colonization to invasive …
diverse range of illnesses. This clinical spectrum from colonization to invasive …
Pneumococcal carriage in children and adults two years after introduction of the thirteen valent pneumococcal conjugate vaccine in England
Abstract Background/Aims In April 2010 the 7-valent pneumococcal conjugate vaccine
(PCV7) was replaced by the 13-valent PCV. We investigated pneumococcal carriage in …
(PCV7) was replaced by the 13-valent PCV. We investigated pneumococcal carriage in …
[HTML][HTML] Whole genome sequencing of Streptococcus pneumoniae: development, evaluation and verification of targets for serogroup and serotype prediction using an …
G Kapatai, CL Sheppard, A Al-Shahib, DJ Litt… - PeerJ, 2016 - peerj.com
Streptococcus pneumoniae typically express one of 92 serologically distinct capsule
polysaccharide (cps) types (serotypes). Some of these serotypes are closely related to each …
polysaccharide (cps) types (serotypes). Some of these serotypes are closely related to each …
Influence of bacterial interactions on pneumococcal colonization of the nasopharynx
Streptococcus pneumoniae (the pneumococcus) is a common commensal inhabitant of the
nasopharynx and a frequent etiologic agent in serious diseases such as pneumonia, otitis …
nasopharynx and a frequent etiologic agent in serious diseases such as pneumonia, otitis …