Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

The development of new and effective antibacterial drugs to treat multi-drug resistant (MDR)
bacteria, especially Gram-negative (G− ve) pathogens, is acknowledged as one of the …

The antibacterial agents currently in clinical development are predominantly derivatives of
well-established antibiotic classes and were selected to address the class-specific …

ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella
pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter …

The antimicrobial resistance crisis is a global health issue requiring discovery and
development of novel therapeutics. However, conventional screening of natural products or …

Carbapenem resistance is a major global health problem that seriously compromises the
treatment of infections caused by nosocomial pathogens. Resistance to carbapenems …

Existing antibacterial agents can be categorized into two generations, but bacterial
insensitivity towards both of these classes poses a serious public health challenge …

The β-lactams have a central place in the antibacterial armamentarium, but the increasing
resistance to these drugs, especially among Gram-negative bacteria, is becoming one of the …

The global burden of bacterial resistance remains one of the most serious public health
concerns. Infections caused by multidrug-resistant (MDR) bacteria in critically ill patients …

Microbial pathogens including Enterobacteriaceae family members bear different antibiotic
resistance genes comprising Extended-Spectrum-ß-Lactamases (ESBLs) and Metallo-ß …