[HTML][HTML] Fabrication of active targeting lipid nanoparticles: Challenges and perspectives
Targeted drug and gene delivery is the key for precision therapy. Lipid nanoparticles as non-
viral vectors have attracted extensive attentions in treating a variety of diseases, such as …
viral vectors have attracted extensive attentions in treating a variety of diseases, such as …
Circular RNAs as therapeutic agents and targets
LM Holdt, A Kohlmaier, D Teupser - Frontiers in physiology, 2018 - frontiersin.org
It has recently been reported that thousands of covalently linked circular RNAs (circRNAs)
are expressed from human genomes. circRNAs emerge during RNA splicing. circRNAs are …
are expressed from human genomes. circRNAs emerge during RNA splicing. circRNAs are …
Oxidative stress and hypertensive diseases
R Loperena, DG Harrison - Medical clinics, 2017 - medical.theclinics.com
It has become clear that reactive oxygen species (ROS) contribute to the development of
hypertension via myriad effects. ROS are essential for normal cell function; however, they …
hypertension via myriad effects. ROS are essential for normal cell function; however, they …
Bacteriophages and phage-inspired nanocarriers for targeted delivery of therapeutic cargos
The main goal of drug delivery systems is to target therapeutic cargoes to desired cells and
to ensure their efficient uptake. Recently a number of studies have focused on designing bio …
to ensure their efficient uptake. Recently a number of studies have focused on designing bio …
E-selectin-targeting delivery of microRNAs by microparticles ameliorates endothelial inflammation and atherosclerosis
E-selectin is a surface marker of endothelial cell (EC) inflammation, one of the hallmarks of
atherogenesis. Thus, we tested the hypothesis that delivery of microRNA (miR)-146a and …
atherogenesis. Thus, we tested the hypothesis that delivery of microRNA (miR)-146a and …
Osteoblast-targeting-peptide modified nanoparticle for siRNA/microRNA delivery
Antiosteoporosis gene-based drug development strategies are presently focused on
targeting osteoblasts to either suppress bone loss or increase bone mass. Although …
targeting osteoblasts to either suppress bone loss or increase bone mass. Although …
Roles of eNOS in atherosclerosis treatment
F Hong, X Liang, W Liu, S Lv, S He, H Kuang… - Inflammation …, 2019 - Springer
Background Atherosclerosis (AS) is the main pathogeny of coronary heart disease, cerebral
infarction and peripheral vascular disease. Endothelial dysfunction is one of the important …
infarction and peripheral vascular disease. Endothelial dysfunction is one of the important …
The critical role of tetrahydrobiopterin (BH4) metabolism in modulating radiosensitivity: BH4/NOS axis as an angel or a devil
Y Feng, Y Feng, L Gu, P Liu, J Cao, S Zhang - Frontiers in Oncology, 2021 - frontiersin.org
Ionizing radiation and radioactive materials have been widely used in industry, medicine,
science and military. The efficacy of radiotherapy and adverse effects of normal tissues are …
science and military. The efficacy of radiotherapy and adverse effects of normal tissues are …
Nanotechnology in diagnosis and treatment of coronary artery disease
Nanotechnology could provide a new complementary approach to treat coronary artery
disease (CAD) which is now one of the biggest killers in the Western world. The course of …
disease (CAD) which is now one of the biggest killers in the Western world. The course of …
Nanotechnology, an alternative with promising prospects and advantages for the treatment of cardiovascular diseases
T Li, W Liang, X Xiao, Y Qian - International journal of …, 2018 - Taylor & Francis
Cardiovascular diseases (CVDs) are one of the most important causes of mortality and
affecting the health status of patients. At the same time, CVDs cause a huge health and …
affecting the health status of patients. At the same time, CVDs cause a huge health and …