Hypervalent iodine reagents are versatile and readily accessible reagents that have been
extensively applied in contemporary synthesis in modern organic chemistry. Among them …

The identity of a heteroatom within an aromatic ring influences the chemical properties of
that heterocyclic compound. Systematically evaluating the effect of a single atom, however …

Skeletal molecular editing gained considerable recent momentum and emerged as a
uniquely powerful tool for late‐stage diversifications. Thus far, superstoichiometric amounts …

The skeletal editing of azaarenes through insertion, deletion, or swapping of single atoms
has recently gained considerable momentum in chemical synthesis. Here, we describe a …

Here, we demonstrate a fundamentally new reactivity of the silyl enol ether functionality
utilizing an in situ-generated iodonitrene-like species. The present transformation inserts a …

Herein we report the development of an oxidative amination process for the streamlined
synthesis of pyridones from cyclopentenones. Cyclopentenone building blocks can undergo …

Single-atom editing, which involves precise modifications to a ring system through the
selective insertion, deletion or substitution of atoms, represents a crucial advancement in the …

A base-promoted nitrogen atom insertion into naphthoquinone rings to construct N-
heterocycles has been described. This approach starts from easily available 2 …

Herein we describe the synthesis of dipyrrolopyrazines via a tandem-Sonogashira coupling
with subsequent direct cyclisation of the resulting bisalkynes. The key precursor, di-tert-butyl …

Molekulares Editieren hat in letzter Zeit stark an Bedeutung gewonnen und sich als
einzigartiges Werkzeug für Late‐Stage Diversifizierungen erwiesen. Bislang waren für die …