Over the course of the past decade, green chemistry has demonstrated how fundamental
scientific methodologies can protect human health and the environment in an economically …

The novel pyrrole/imidazole alkaloids solsodomine A 1 and B 2 have been isolated from
fresh berries of Solanum sodomaeum L., collected from the Libyan desert. 1 This is the first …

The use of polymer-supported reagents and scavengers provides an attractive and practical
method for the clean and efficient preparation of novel chemical libraries with potential …

In both lead identification and lead optimization processes there is an acute need for new
organic small molecules. Traditional methods of organic synthesis are orders of magnitude …

The shift of paradigm in combinatorial chemistry, from large compound libraries (of mixtures)
on a small scale towards defined compound libraries where each compound is prepared in …

As part of the dramatic changes associated with the need for preparing compound libraries
in pharmaceutical and agrochemical research laboratories, industry searches for new …

The increasing need to efficiently assemble small molecules as potential modulators of
therapeutic targets that are emerging from genomics and proteomics is driving the …

There has been a wealth of recent reports concerning support-bound reagents and
scavengers in the solution-phase synthesis of compound libraries and natural products …

Oxidative biaryl coupling reaction of phenol ether derivatives with the hypervalent iodine
reagent, phenyliodine (III) bis (trifluoroacetate)(PIFA), in the presence of BF3· Et2O gave a …

Abstract Eine umweltschonende Oxidation von Alkoholen in Wasser mit Iodosobenzol (PhI=
O) oder polymergebundenem (Diacetoxyiodo) benzol (PSDIB) wurde in Gegenwart von KBr …