[HTML][HTML] Advances in the interaction between endoplasmic reticulum stress and osteoporosis

M Zhong, Z Wu, Z Chen, Q Ren, J Zhou - Biomedicine & Pharmacotherapy, 2023 - Elsevier
The endoplasmic reticulum (ER) is the main site for protein synthesis, folding, and secretion,
and accumulation of the unfolded/misfolded proteins in the ER may induce ER stress. ER …

Role of activating transcription factor 3 and its interacting proteins under physiological and pathological conditions

M Rohini, AH Menon, N Selvamurugan - International journal of biological …, 2018 - Elsevier
Abstract Activating transcription factor 3 (ATF3) is a stress-responsive factor that belongs to
the activator protein 1 (AP-1) family of transcription factors. ATF3 expression is stimulated by …

Curcumin induces osteoblast differentiation through mild-endoplasmic reticulum stress-mediated such as BMP2 on osteoblast cells

HE Son, EJ Kim, WG Jang - Life sciences, 2018 - Elsevier
Aims Curcumin (diferuloylmethane or [1E, 6E]-1, 7-bis [4-hydroxy-3-methoxyphenyl]-1,
6heptadiene-3, 5-dione) is a phenolic natural product derived from the rhizomes of the …

Decreased MORF leads to prolonged endoplasmic reticulum stress in periodontitis-associated chronic inflammation

P Xue, B Li, Y An, J Sun, X He, R Hou, G Dong… - Cell Death & …, 2016 - nature.com
The association between inflammation and endoplasmic reticulum (ER) stress has been
described in many diseases. However, if and how chronic inflammation governs the …

[HTML][HTML] Apabetalone downregulates factors and pathways associated with vascular calcification

D Gilham, LM Tsujikawa, CD Sarsons, C Halliday… - Atherosclerosis, 2019 - Elsevier
Background and aims Apabetalone is an inhibitor of bromodomain and extraterminal (BET)
proteins. In clinical trials, apabetalone reduced the incidence of major adverse cardiac …

Single‐cell RNA sequencing reveals the CRTAC1+ population actively contributes to the pathogenesis of spinal ligament degeneration by SPP1+ macrophage

Y Tang, D Zhuo, Y Yu, W Pu, Y Ma, Y Zhang… - Aging …, 2024 - Wiley Online Library
Degenerative spinal stenosis is a chronic disease that affects the spinal ligaments and
associated bones, resulting in back pain and disorders of the limbs among the elderly …

[HTML][HTML] miR-27a-3p targets ATF3 to reduce calcium deposition in vascular smooth muscle cells

N Choe, DH Kwon, J Ryu, S Shin, HJ Cho… - … Therapy-Nucleic Acids, 2020 - cell.com
Vascular calcification, the ectopic deposition of calcium in blood vessels, develops in
association with various metabolic diseases and atherosclerosis and is an independent …

miR‐342‐3p promotes osteogenic differentiation via targeting ATF 3

Y Han, K Zhang, Y Hong, J Wang, Q Liu, Z Zhang… - FEBS …, 2018 - Wiley Online Library
Through their multiple targets, micro RNA s (mi RNA s) are involved in numerous
physiological and pathological processes. In this study, miR‐342‐3p was found to be …

[HTML][HTML] Epigenetic modifications in spinal ligament aging

Q Xiang, Y Zhao, J Lin, S Jiang, W Li - Ageing Research Reviews, 2022 - Elsevier
Spinal stenosis is a common degenerative spine disorder in the aged population and the
spinal ligament aging is a main contributor to this chronic disease. However, the underlying …

Effects of weaning on intestinal longitudinal muscle-myenteric plexus function in piglets

J Li, F Liu, K Mo, H Ni, Y Yin - Science China Life Sciences, 2024 - Springer
Weaning piglets usually suffer from severe diarrhea (commonly known as postweaning
diarrhea, PWD) along with intestinal motility disorder. Intestinal peristalsis is mainly …