COVID-19 in dialysis: clinical impact, immune response, prevention, and treatment

K El Karoui, AS De Vriese - Kidney International, 2022 - Elsevier
The COVID-19 pandemic has profound adverse effects on the population on dialysis.
Patients requiring dialysis are at an increased risk of SARS-CoV-2 infection and mortality …

[HTML][HTML] Crosstalk between the renin–angiotensin, complement and kallikrein–kinin systems in inflammation

Z Bekassy, I Lopatko Fagerström, M Bader… - Nature Reviews …, 2022 - nature.com
During severe inflammatory and infectious diseases, various mediators modulate the
equilibrium of vascular tone, inflammation, coagulation and thrombosis. This Review …

Role of Hypertension on the Severity of COVID-19: A Review

M Peng, J He, Y Xue, X Yang, S Liu… - Journal of …, 2021 - journals.lww.com
The novel coronavirus disease (COVID-19) caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has rapidly evolved into a global pandemic. The …

Blood pressure control among US adults, 2009 to 2012 through 2017 to 2020

P Muntner, MA Miles, BC Jaeger, L Hannon Iii… - …, 2022 - Am Heart Assoc
Background: The National Health and Nutrition Examination Survey data indicate that the
proportion of US adults with hypertension that had controlled blood pressure (BP) declined …

Arterial hypertension–Clinical trials update 2021

H Al Ghorani, F Goetzinger, M Boehm… - Nutrition, Metabolism and …, 2022 - Elsevier
Aim This review aims to summarize and discuss some of the most relevant clinical trials in
epidemiology, diagnostics, and treatment of hypertension published in 2020 and 2021. Data …

[HTML][HTML] Chronic diseases, health conditions and risk of COVID-19-related hospitalization and in-hospital mortality during the first wave of the epidemic in France: a …

L Semenzato, J Botton, J Drouin, F Cuenot… - The Lancet Regional …, 2021 - thelancet.com
Background From the beginning of the COVID-19 pandemic, age (most importantly), male
gender and various comorbidities were found to be associated with severe forms of COVID …

[HTML][HTML] Angiotensin-Converting Enzyme 2 (ACE2) in the Pathogenesis of ARDS in COVID-19

K Kuba, T Yamaguchi, JM Penninger - Frontiers in immunology, 2021 - frontiersin.org
Seventeen years after the epidemic of SARS coronavirus, a novel coronavirus SARS-CoV-2-
emerged resulting in an unprecedented pandemic. Angiotensin-converting enzyme 2 …

Efficacy of losartan in hospitalized patients with COVID-19–induced lung injury: a randomized clinical trial

MA Puskarich, NE Ingraham, LH Merck… - JAMA network …, 2022 - jamanetwork.com
Importance SARS-CoV-2 viral entry may disrupt angiotensin II (AII) homeostasis,
contributing to COVID-19 induced lung injury. AII type 1 receptor blockade mitigates lung …

A modified self‐controlled case series method for event‐dependent exposures and high event‐related mortality, with application to COVID‐19 vaccine safety

Y Ghebremichael‐Weldeselassie… - Statistics in …, 2022 - Wiley Online Library
We propose a modified self‐controlled case series (SCCS) method to handle both event‐
dependent exposures and high event‐related mortality. This development is motivated by an …

[HTML][HTML] Functional ACE2 deficiency leading to angiotensin imbalance in the pathophysiology of COVID-19

JR Cook, J Ausiello - Reviews in Endocrine and Metabolic Disorders, 2022 - Springer
Abstract SARS-CoV-2, the virus responsible for COVID-19, uses angiotensin converting
enzyme 2 (ACE2) as its primary cell-surface receptor. ACE2 is a key enzyme in the counter …