The proliferation of increasingly more sophisticated analytical separation systems, often
incorporating increasingly more powerful detection techniques, such as high‐resolution …

Highlights•Recent LC–MS and GC–MS methods are reviewed.•The use of multiple columns
extends the coverage of the metabolome.•Super critical fluid chromatography (SFC) could …

The term non-targeted metabolomics implies a global and unbiased analysis. This involves
the complex (and yet not routine) task of correct alignment and eventually annotation of …

Two-dimensional liquid chromatography (2D-LC) is becoming increasingly popular for the
analysis of complex samples, which is partly due to the recent introduction of commercial 2D …

Liquid chromatography with single columns often does not succeed in the analysis of
complex samples, in terms of resolution and analysis time. A relatively simple solution to …

The lack of suitable chromatographic purification methods makes it a challenge to effectively
isolate the chemical components of traditional Tibetan medicines. Ribes himalense is a …

Introduction Screening and analysis of bioactive components from natural products is a
fundamental part of new drug development and innovation. Two‐dimensional (2D) …

In-silico optimisation of a two-dimensional high performance liquid chromatography (2D-
HPLC) separation protocol has been developed for the interrogation of methamphetamine …

While data processing methods in metabolomic studies often work with'n'number of
dimensions, analytical techniques, with the notable exception of NMR, have mostly stuck …

In this study,“two dimensional” molecularly imprinted solid-phase extraction (2D-MIP-SPE) of
semi-preparative grade was constructed to fast purify ellagitannins in pomegranate husk …