[HTML][HTML] Recent progress of hypoxia-modulated multifunctional nanomedicines to enhance photodynamic therapy: opportunities, challenges, and future development

Y Sun, D Zhao, G Wang, Y Wang, L Cao, J Sun… - … Pharmaceutica Sinica B, 2020 - Elsevier
Hypoxia, a salient feature of most solid tumors, confers invasiveness and resistance to the
tumor cells. Oxygen-consumption photodynamic therapy (PDT) suffers from the undesirable …

Responsive fluorescent probes for cellular microenvironment and redox small biomolecules

L Zhang, L Zhang, X Zhang, Y Zhao, S Fang… - TrAC Trends in …, 2023 - Elsevier
The living system is critically depended on the inner microenvironment and redox small
biomolecules to maintain the normal physiological processes. Consequently, tracing and …

Turn-on fluorescent biosensors for imaging hypoxia-like conditions in living cells

S Guisán-Ceinos, A R. Rivero… - Journal of the …, 2022 - ACS Publications
We present the synthesis, photophysical properties, and biological application of nontoxic 3-
azo-conjugated BODIPY dyes as masked fluorescent biosensors of hypoxia-like conditions …

Current developments in nanotechnology for improved cancer treatment, focusing on tumor hypoxia

C Dai Phung, TH Tran, HT Nguyen, JH Jeong… - Journal of Controlled …, 2020 - Elsevier
Hypoxia is a common feature of the tumor microenvironment, which is characterized by
tissue oxygen deficiency due to an aggressive proliferation of cancer cells. Hypoxia …

Reductive metabolism of azo dyes and drugs: Toxicological implications

PD Josephy, E Allen-Vercoe - Food and Chemical Toxicology, 2023 - Elsevier
Azo compounds are widely distributed synthetic chemicals in the modern world. Their most
important applications are as dyes, but, in addition, several azo compounds are used as …

Vascular disrupting agents in cancer therapy

R Smolarczyk, J Czapla, M Jarosz-Biej… - European Journal of …, 2021 - Elsevier
Tumor blood vessel formation is a key process for tumor expansion. Tumor vessels are
abnormal and differ from normal vessels in architecture and components. Besides oxygen …

Recent applications of azo dyes: A paradigm shift from medicinal chemistry to biomedical sciences

MN Khan, DK Parmar, D Das - Mini Reviews in Medicinal …, 2021 - ingentaconnect.com
Azo molecules possess the characteristic azo bond (-N= N-) and are considered fascinating
motifs in organic chemistry. Since the last century, these brightly colored compounds have …

Recent advances in ZnO-based photosensitizers: Synthesis, modification, and applications in photodynamic cancer therapy

H Fatima, ZY Jin, Z Shao, XJ Chen - Journal of Colloid and Interface …, 2022 - Elsevier
Abstract Zinc oxide nanoparticles (ZnO NPs) are important semiconductor materials with
interesting photo-responsive properties. During the past, ZnO-based NPs have received …

State of the art in carbon nanomaterials for photoacoustic imaging

MS Kang, H Lee, SJ Jeong, TJ Eom, J Kim, DW Han - Biomedicines, 2022 - mdpi.com
Photoacoustic imaging using energy conversion from light to ultrasound waves has been
developed as a powerful tool to investigate in vivo phenomena due to their complex …

Nano versus molecular: Optical imaging approaches to detect and monitor tumor hypoxia

MHY Cheng, Y Mo, G Zheng - Advanced Healthcare Materials, 2021 - Wiley Online Library
Hypoxia is a ubiquitous feature of solid tumors, which plays a key role in tumor angiogenesis
and resistance development. Conventional hypoxia detection methods lack continuous …