Heteroaryl–Heteroaryl Suzuki–Miyaura Cross-Coupling Enabled by Large-but-Flexible Dibenzobarrelene-Derived Pd-NHC Precatalysts

M Guo, Y Zhang, MJ Zhang, T Li, JY Wu, FS Liu - Organometallics, 2023 - ACS Publications
The present study describes a class of “large-but-flexible” Pd-NHC complexes derived from
dibenzobarrelene. These complexes have been successfully employed in Pd-catalyzed …

Halide Salts Alleviate TMSOK Inhibition in Suzuki–Miyaura Cross-Couplings

Y Shi, JS Derasp, SM Guzman, BO Patrick… - ACS catalysis, 2024 - ACS Publications
The Suzuki–Miyaura cross-coupling (SMC) remains one of the most widely used
transformations available to chemists. Recently, robust new conditions achieving rapid …

Weak Base-Promoted Direct Cross-Coupling of Naphthalene-1, 8-diaminato-substituted Arylboron Compounds

K Tomota, J Li, H Tanaka, M Nakamoto, T Tsushima… - JACS Au, 2024 - ACS Publications
The indispensability of a base in Suzuki–Miyaura coupling (SMC) employing organoboronic
acids/esters is well recognized, which occasionally induces competitive protodeborylation in …

[HTML][HTML] Organoselenium compounds from purines: synthesis of 6-arylselanylpurines with antioxidant and anticholinesterase activities and memory improvement effect

LFB Duarte, RL Oliveira, KC Rodrigues, GT Voss… - Bioorganic & medicinal …, 2017 - Elsevier
We describe here a simple method for the synthesis of 6-arylselanylpurines with antioxidant
and anticholinesterase activities, and memory improvement effect. This class of compounds …

Direct synthesis of alkenylboronates from alkenes and pinacol diboron via copper catalysis

W Lu, Z Shen - Organic letters, 2018 - ACS Publications
We report an efficient approach for the direct synthesis of alkenylboronates using copper
catalysis. The Cu/TEMPO catalyst system (where TEMPO=(2, 2, 6, 6-tetramethylpiperidin-1 …

Highly Fluorescent 2‐Aminopurine Derivatives: Synthesis, Photo‐physical Characterization, and Preliminary Cytotoxicity Evaluation

JM Gonçalves, JND Gonçalves, AS Pêra… - European Journal of …, 2023 - Wiley Online Library
New fluorescent nucleobase analogues (FBAs) are emerging as extraordinarily useful tools
for DNA labelling technologies. The highly fluorescent adenine analogue 2‐aminopurine …

Synthesis of C6-substituted purine nucleoside analogues via late-stage photoredox/nickel dual catalytic cross-coupling

JJ Perkins, VW Shurtleff, AM Johnson… - ACS Medicinal …, 2021 - ACS Publications
Nucleoside analogues have been and continue to be extremely important compounds in
drug discovery. Despite the significant effort dedicated to their synthesis, medicinal …

Synthesis of Fluorescent C–C Bonded Triazole-Purine Conjugates

A Burcevs, A Sebris, K Traskovskis, HW Chu… - Journal of …, 2024 - Springer
Abstract A design toward C–C bonded 2, 6-bis (1 H-1, 2, 3-triazol-4-yl)-9 H-purine and 2-
piperidinyl-6-(1 H-1, 2, 3-triazol-4-yl)-9 H-purine derivatives was established using the …

[HTML][HTML] Na2 [Pd (saccharinate) 4]: A new phosphine-free water-soluble catalyst with singular structure for modification of ribose nucleosides at room temperature

JL Serrano, J Pérez, JA Pérez, I da Silva, R Sahu, K Pal… - Catalysis Today, 2024 - Elsevier
The easy synthesis of the anionic palladium catalyst containing saccharinate as only ligand
Na 2 [Pd (saccharinate) 4](I), starting from either Na 2 [PdCl 4] or Pd (AcO) 2, is reported …

Brønsted Acid‐Catalyzed Direct C(sp2)−H Heteroarylation Enabling the Synthesis of Structurally Diverse Biaryl Derivatives

S Yuan, B Yu, HM Liu - Advanced Synthesis & Catalysis, 2019 - Wiley Online Library
Biaryl scaffold is an important class of structural frameworks that exists in many natural
products and drug molecules. The development of transition metal‐catalyzed approaches …