Calcific aortic valve disease (CAVD) is the most common disorder affecting heart valves and
is characterized by thickening, fibrosis and mineralization of the aortic valve leaflets …

Cadherin family includes lists of transmembrane glycoproteins which mediate calcium-
dependent cell-cell adhesion. Cadherin-mediated adhesion regulates cell growth and …

Metastasis accounts for 90% of cancer-related deaths among the patients. The
transformation of epithelial cells into mesenchymal cells with molecular alterations can occur …

Although most breast cancer metastases in bone cause osteolytic lesions, the osteogenic
niche has commonly been described as an initiator of early-stage bone colonization of …

Background There is a critical need to better understand the mechanisms that drive local cell
invasion and metastasis to develop new therapeutics targeting metastatic disease …

Bone is one of the most common metastatic sites among breast cancer (BC) patients. Once
bone metastasis is developed, patients' survival and quality of life will be significantly …

Since the discovery of breast cancer stem cells (CSCs), a significant effort has been made to
identify and characterize these cells. It is a generally believe that CSCs play an important …

Background Triple-negative breast cancer (TNBC) is the most heterogeneous and malignant
subtype of breast cancer (BC). TNBC is defined by the absence of expression of estrogen …

Simple Summary Cancer stem cells (CSCs) in breast cancer have been identified for almost
two decades. Many outstanding discoveries have established the important functions of …

Cadherin is an important cell-cell adhesion molecule, which mediates intercellular adhesion
through calcium dependent affinity interaction. Cadherin-11 (CDH11, OB-cadherin) is a …