Single-cell sequencing (SCS) has emerged as a powerful new set of technologies for
studying rare cells and delineating complex populations. Over the past 5 years, SCS …

Over the last 60 years, soil microbiologists have accumulated a wealth of experimental data
showing that the bulk, macroscopic parameters (eg, granulometry, pH, soil organic matter …

Intestinal Th17 cells are induced and accumulate in response to colonization with a
subgroup of intestinal microbes such as segmented filamentous bacteria (SFB) and certain …

Extensive genomic diversity within coexisting members of a microbial species has been
revealed through selected cultured isolates and metagenomic assemblies. Yet, the cell-by …

Background A vast diversity of microbes colonizes in the human gastrointestinal tract,
referred to intestinal microbiota. Microbiota and products thereof are indispensable for …

Interest in the expanding catalog of uncultivated microorganisms, increasing recognition of
heterogeneity among seemingly similar cells, and technological advances in whole-genome …

Complex microbial communities are an integral part of the Earth's ecosystem and of our
bodies in health and disease. In the last two decades, culture‐independent approaches …

Single-cell whole-transcriptome analysis is a powerful tool for quantifying gene expression
heterogeneity in populations of cells. Many techniques have, thus, been recently developed …

Background Sufficient exposure to natural environments, in particular soil and its microbes,
has been suggested to be protective against allergies. Objective We aim at gaining more …

Single cell genomics (SCG) uncovers hereditary information at the most basic level of
biological organization. It is emerging as a powerful complement to cultivation-based and …