The nuclear genomes of vertebrates are mosaics of isochores, very long stretches (≫
300kb) of DNA that are homogeneous in base composition and are compositionally …

The term genome was first introduced by German botanist Hans Winkler in the early 19th
century to describe the eukaryotic chromosome. It gained considerable attention through the …

Linear correlations exist between the GC levels of third codon positions (GC3) of individual
human genes and the GC levels of long genomic sequences and DNA molecules (50–100 …

The human genome is made up of long DNA segments, the isochores, which are
compositionally homogeneous and can be subdivided into a small number of families …

This review will first present some properties (including compositional pattern, correlations
between isochores and chromosomal bands, and gene distribution) of the human genome …

A YAC/STS map of the X chromosome has reached an inter-STS resolution of 75 kb. The
map density is sufficient to provide YACs or other large-insert clones that are cross-validated …

Analytical DNA ultracentrifugation revealed that eukaryotic genomes are mosaics of
isochores: long DNA segments (≫ 300 kb on average) relatively homogeneous in G+ C …

The human genome is a mosaic of isochores, long DNA segments which are
compositionally homogeneous and which can be partitioned into five families, L1, L2, H1 …

The human genome is composed of long-range G+ C%(GC%) mosaic structures thought to
be related to chromosome bands. We previously reported a boundary of megabase-sized …

Recent advances have been made in addressing three intriguing aspects of human genome
organization: the organization of protein-coding sequences within chromosomes, the …