Background Several studies have found only a weak to moderate correlation between
oxygenation and lung aeration in response to changes in PEEP. This study aimed to …

Background: Arterial oxygenation is often impaired during one-lung ventilation, due to both
pulmonary shunt and atelectasis. The use of low tidal volume (VT)(5 ml/kg predicted body …

This review paper identifies benefits from various Decision Support Systems (DSSs) and
introduces a range of examples from the literature. Those examples are organized …

Computer simulation offers a fresh approach to traditional medical research that is
particularly well suited to investigating issues related to mechanical ventilation. Patients …

Objectives: To evaluate the physiologic effects of applying advice on mechanical ventilation
by an open-loop, physiologic model–based clinical decision support system. Design …

Background Weaning is typically regarded as a process of discontinuing mechanical
ventilation in the daily practice of an intensive care unit (ICU). Among the ICU patients, 39 …

Our education system seems to fail to enable clinicians to broadly understand core
physiological principles. The emphasis on reductionist science, including “omics” branches …

Mathematical physiological models can be applied in medical decision support systems. To
do so requires consideration of the necessary model complexity. Models that simulate …

Computerized decision support (CDS) is the most advanced form of clinical decision support
available and has evolved with innovative technologies to provide meaningful assistance to …

Mechanical ventilation is a very effective therapy, but with many complications. Simulators
are used in many fields, including medicine, to enhance safety issues. In the intensive care …