The multiple endocrine functions of bone other than those related to mineral metabolism,
such as regulation of insulin sensitivity, glucose homeostasis, and energy metabolism, have …

Diabesity is the combination of type 2 diabetes and obesity characterized by chronic low-
grade inflammation. The Wnt signaling act as an evolutionary pathway playing crucial role in …

WNT signaling was discovered in tumor models and has been recognized as a regulator of
cancer development and progression for over 3 decades. Recent work has highlighted a …

Enhancing β-cell proliferation is a major goal for type 1 and type 2 diabetes research.
Unraveling the network of β-cell intracellular signaling pathways that promote β-cell …

Accelerated glucose metabolism is critical in hepatocarcinogenesis, but the utilities of
different glucose transporter inhibitors in treating hepatocellular carcinoma (HCC) remain …

The neuroendocrine hypothalamus is composed of the tuberal and anterodorsal
hypothalamus, together with the median eminence/neurohypophysis. It centrally governs …

Although high-fat diet (HFD) has been implicated in the development of colorectal cancer
(CRC), the critical signaling molecule that mediates the cancer growth is not well-defined …

Materials and Methods: HepG2 cells were treated with different doses of CAN and then
exposed to different doses of γ-IR to achieve optimization that was based on cytotoxicity and …

Diabetes mellitus is a metabolic disorder that causes health concerns worldwide. Patients
with diabetes exhibit multisystemic symptoms, including loss of bone quality over time. The …

The medial hypothalamus is composed of nuclei of the tuberal hypothalamus, the
paraventricular nucleus of the anterior hypothalamus, and the neurohypophysis. Its …