Turning the page: advancing paper-based microfluidics for broad diagnostic application

MM Gong, D Sinton - Chemical reviews, 2017 - ACS Publications
Infectious diseases are a major global health issue. Diagnosis is a critical first step in
effectively managing their spread. Paper-based microfluidic diagnostics first emerged in …

Nitrocellulose membrane for paper-based biosensor

R Tang, MY Xie, M Li, L Cao, S Feng, Z Li, F Xu - Applied Materials Today, 2022 - Elsevier
Biosensor provides a useful tool for earlier diagnosis of disease, food safety and
environment monitoring at resource-limited settings. Paper is green and porous material and …

Platinum nanocatalyst amplification: redefining the gold standard for lateral flow immunoassays with ultrabroad dynamic range

CN Loynachan, MR Thomas, ER Gray, DA Richards… - ACS …, 2018 - ACS Publications
Paper-based lateral flow immunoassays (LFIAs) are one of the most widely used point-of-
care (PoC) devices; however, their application in early disease diagnostics is often limited …

Glycosylated gold nanoparticles in point of care diagnostics: From aggregation to lateral flow

AN Baker, GW Hawker-Bond, PG Georgiou… - Chemical Society …, 2022 - pubs.rsc.org
Current point-of-care lateral flow immunoassays, such as the home pregnancy test, rely on
proteins as detection units (eg antibodies) to sense for analytes. Glycans play a fundamental …

A low-cost nanomaterial-based electrochemical immunosensor on paper for high-sensitivity early detection of pancreatic cancer

KS Prasad, X Cao, N Gao, Q Jin, ST Sanjay… - Sensors and Actuators B …, 2020 - Elsevier
Due to the lack of specific early detection methods for pancreatic cancer, it usually goes
undetected until it is advanced. By employing paper-based electrodes (PPEs), herein we for …

Site-selective orientated immobilization of antibodies and conjugates for immunodiagnostics development

M Shen, JF Rusling, CK Dixit - Methods, 2017 - Elsevier
Immobilized antibody systems are the key to develop efficient diagnostics and separations
tools. In the last decade, developments in the field of biomolecular engineering and …

Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site

EM Strauch, SM Bernard, D La, AJ Bohn, PS Lee… - Nature …, 2017 - nature.com
Many viral surface glycoproteins and cell surface receptors are homo-oligomers,,,, and thus
can potentially be targeted by geometrically matched homo-oligomers that engage all …

3D capillary-driven paper-based sequential microfluidic device for electrochemical sensing applications

A Yakoh, S Chaiyo, W Siangproh, O Chailapakul - ACS sensors, 2019 - ACS Publications
This article describes the device design and fabrication of two different configurations (flow-
through and stopped-flow) of a sequential fluid delivery platform on a microfluidic paper …

Paper microfluidic device for early diagnosis and prognosis of acute myocardial infarction via quantitative multiplex cardiac biomarker detection

WY Lim, TM Thevarajah, BT Goh, SM Khor - Biosensors and Bioelectronics, 2019 - Elsevier
The early detection of acute myocardial infarction (AMI) upon the onset of chest pain
symptoms is crucial for patient survival. However, this detection is challenging, particularly …

Passive micropumping in microfluidics for point-of-care testing

L Xu, A Wang, X Li, KW Oh - Biomicrofluidics, 2020 - pubs.aip.org
Suitable micropumping methods for flow control represent a major technical hurdle in the
development of microfluidic systems for point-of-care testing (POCT). Passive micropumping …