Ferroptosis, a form of regulated cell death, is characterized by an excessive degree of iron
accumulation and lipid peroxidation. Although it was originally identified only in cells …

The transcription factor family activator protein 2 (TFAP2) is vital for regulating both
embryonic and oncogenic development. The TFAP2 family consists of five DNA-binding …

Testicular germ cell tumours (TGCTs) rank as the most common malignancy in men aged 20‐
34 years, and seminomas are the most type of TGCTs. As a crucial anti‐tumour agent with …

Abstract The Activator Protein 2 (AP-2) transcription factor (TF) family is vital for the
regulation of gene expression during early development as well as carcinogenesis process …

Background Aberrant expression of transcription Factor AP-2 Gamma (TFAP2C) has been
reported to be implicated in malignant process of many cancers. The purpose of this study is …

Transcription factors are known to mediate the conversion of somatic cells to induced
pluripotent stem cells (iPSCs). Transcription factor TFAP2C plays important roles in the …

DO, Hyunhee et al. TFAP2C increases cell proliferation by downregulating GADD45B and
PMAIP1 in non-small cell lung cancer cells. Biol. Res.[online]. 2019, vol. 52, 35. Epub 26-Jul …

Breast cancer (BC) formation is primarily influenced by genetics, epigenetics and
environmental factors. Aberrant Genetics and epigenetics leads to a condition known as …

Ferroptosis is a newly discovered programmed cell death that plays a vital role in the
occurrence and development of tumors. However, little is known about its prognostic value …

One goal of precision medicine is to tailor effective treatments to patients' specific molecular
markers of disease. Here, we used mass cytometry to characterize the single-cell signaling …