On the origin of sugar handedness: facts, hypotheses and missing links-a review

RF Martínez, LA Cuccia, C Viedma, P Cintas - Origins of Life and Evolution …, 2022 - Springer
By paraphrasing one of Kipling's most amazing short stories (How the Leopard Got His
Spots), this article could be entitled “How Sugars Became Homochiral”. Obviously, we have …

Thermal Synthesis of Carbamic Acid and Its Dimer in Interstellar Ices: A Reservoir of Interstellar Amino Acids

JH Marks, J Wang, BJ Sun, M McAnally… - ACS central …, 2023 - ACS Publications
Reactions in interstellar ices are shown to be capable of producing key prebiotic molecules
without energetic radiation that are necessary for the origins of life. When present in …

Aldehyde catalysis–from simple aldehydes to artificial enzymes

Z Yuan, J Liao, H Jiang, P Cao, Y Li - RSC advances, 2020 - pubs.rsc.org
Chemists have been learning and mimicking enzymatic catalysis in various aspects of
organic synthesis. One of the major goals is to develop versatile catalysts that inherit the …

Interstellar formation of lactaldehyde, a key intermediate in the methylglyoxal pathway

J Wang, C Zhang, JH Marks, MM Evseev… - Nature …, 2024 - nature.com
Aldehydes are ubiquitous in star-forming regions and carbonaceous chondrites, serving as
essential intermediates in metabolic pathways and molecular mass growth processes to vital …

Interstellar formation of biorelevant pyruvic acid (CH3COCOOH)

NF Kleimeier, AK Eckhardt, PR Schreiner, RI Kaiser - Chem, 2020 - cell.com
Pyruvic acid represents a key molecule in prebiotic chemistry to form metabolites and amino
acids. Without liquid water on the early Earth, endogenous formation of pyruvic acid is …

Unraveling sulfur chemistry in interstellar carbon oxide ices

X Li, B Lu, L Wang, J Xue, B Zhu, T Trabelsi… - Nature …, 2022 - nature.com
Formyl radical (HCO•) and hydroxycarbonyl radical (HOCO•) are versatile building blocks in
the formation of biorelevant complex organic molecules (COMs) in interstellar medium …

Quantum-tunneling-mediated synthesis of prebiotic chelation agents in interstellar analog ices

JH Marks, AA Nikolayev, MM Evseev, J Wang… - Chem, 2023 - cell.com
Ion transport is vital to all modern lifeforms, but how early cells could have accomplished this
without complex proteins that are used by modern cells has remained elusive. Here, we …

Effects of geochemical and environmental parameters on abiotic organic chemistry driven by iron hydroxide minerals

LM Barge, E Flores, DG VanderVelde… - Journal of …, 2020 - Wiley Online Library
Geological conditions play a significant role in prebiotic/abiotic organic chemistry, especially
when reactive minerals are present. Previous studies of the prebiotic synthesis of amino …

H-atom-assisted formation of key radical intermediates in interstellar sugar synthesis-New insights from para-H2 matrix isolation experiments

B Keresztes, B Aazaad, A Schneiker, S Góbi… - Astronomy & …, 2024 - aanda.org
Context. Despite the identification of the smallest sugar molecule, glycolaldehyde (GA), in
the interstellar medium (ISM), its mechanism of formation in the ISM is still not fully …

Prebiotic reactions in a Mars analog iron mineral system: effects of nitrate, nitrite, and ammonia on amino acid formation

LM Barge, E Flores, JM Weber, AA Fraeman… - … et Cosmochimica Acta, 2022 - Elsevier
Iron minerals are highly reactive drivers of abiotic/prebiotic organic chemistry, and in the
presence of ammonia (NH 3/NH 4+) or other reduced nitrogen (N) compounds, have been …