Today, Fmoc SPPS is the method of choice for peptide synthesis. Very‐high‐quality Fmoc
building blocks are available at low cost because of the economies of scale arising from …

Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …

A wide spectrum of metabolites (mainly, the three major nutrients and their derivatives) can
be sensed by specific sensors, then trigger a series of signal transduction pathways and …

MusiteDeep is an online resource providing a deep-learning framework for protein post-
translational modification (PTM) site prediction and visualization. The predictor only uses …

Recombinant protein production emerged in the early 1980s with the development of
genetic engineering tools, which represented a compelling alternative to protein extraction …

A surprise revealed by the success of the human genome project was the lower-than-
anticipated number of genes identified:∼ 20,300, rather than the∼ 100,000 estimated 1 …

Post-translational modifications (PTMs) are at the heart of many cellular signaling events.
Apart from a single regulatory PTM, there are also PTMs that function in orchestrated …

Despite decades of accumulated knowledge about proteins and their post-translational
modifications (PTMs), numerous questions remain regarding their molecular composition …

Protein posttranslational modifications (PTMs) refer to the breaking or generation of covalent
bonds on the backbones or amino acid side chains of proteins and expand the diversity of …

Motivation Computational methods for phosphorylation site prediction play important roles in
protein function studies and experimental design. Most existing methods are based on …