Glial cells, including astrocytes, oligodendrocytes, and microglia, are the major components
in the central nervous system (CNS). Studies have revealed the heterogeneity of each glial …

Microglia are the resident immune cells of the central nervous system, and are important for
cellular processes. In addition to their classical roles in pathophysiological conditions, these …

As the mammalian central nervous system matures, its regenerative ability decreases,
leading to incomplete or non‐recovery from the neurodegenerative diseases and central …

Clearance of myelin debris caused by acute demyelination is an essential process for
functional restoration following spinal cord injury (SCI). Microvascular endothelial cells …

Spinal cord injury (SCI) results in stalled motor function recovery under the chronic phase.
One of the reasons due to the presence of ongoing inflammation. Therefore, regulating the …

Intractable neuropathic pain following spinal cord injury (NP-SCI) reduces a patient's quality
of life. Excessive release of ATP into the extracellular space evokes neuroinflammation via …

Abstract Lipocalin 2 (LCN2), an immunomodulator, regulates various cellular processes
such as iron transport and defense against bacterial infection. Under pathological …

Spinal cord injury (SCI) is a catastrophic accidence with little effective treatment, and
inflammation played an important role in that. Previous studies showed photobiomodulation …

Spinal cord injury (SCI) is a common clinical problem in orthopedics with a lack of effective
treatments and drug targets. In the present study, we performed bioinformatic analysis of SCI …

Reactive astrogliosis and inflammation are pathologic hallmarks of spinal cord injury. After
injury, dysfunction of glial cells (astrocytes) results in glial scar formation, which limits …