SARS-CoV-2 resistance to monoclonal antibodies and small-molecule drugs
S Iketani, DD Ho - Cell Chemical Biology, 2024 - cell.com
Over four years have passed since the beginning of the COVID-19 pandemic. The scientific
response has been rapid and effective, with many therapeutic monoclonal antibodies and …
response has been rapid and effective, with many therapeutic monoclonal antibodies and …
Application of a Receptor-Binding-Domain-Based Simple Immunoassay for Assessing Humoral Immunity against Emerging SARS-CoV-2 Virus Variants
We have developed a simple, rapid, high-throughput RBD-based ELISA to assess the
humoral immunity against emerging SARS-CoV-2 virus variants. The cDNAs of the His …
humoral immunity against emerging SARS-CoV-2 virus variants. The cDNAs of the His …
Influenza A virus resistance to 4'-fluorouridine coincides with viral attenuation in vitro and in vivo
CM Lieber, HJ Kang, M Aggarwal, NA Lieberman… - Plos …, 2024 - journals.plos.org
Pre-existing or rapidly emerging resistance of influenza viruses to approved antivirals makes
the development of novel therapeutics to mitigate seasonal influenza and improve …
the development of novel therapeutics to mitigate seasonal influenza and improve …
Clinical phenotype and outcome of persistent SARS-CoV-2 replication in immunocompromised hosts: a retrospective observational study in the Omicron era
V Götz, P Mathé, P Agarwal, D Hornuss, S Pfau… - Infection, 2023 - Springer
Purpose This study aims to describe clinical, virological and radiological characteristics as
well as treatment strategies and outcomes of immunocompromised patients with persistent …
well as treatment strategies and outcomes of immunocompromised patients with persistent …
SARS-CoV-2 variants from long-term, persistently infected immunocompromised patients have altered syncytia formation, temperature-dependent replication, and …
C Wouters, J Sachithanandham, E Akin, L Pieterse… - bioRxiv, 2024 - biorxiv.org
SARS-CoV-2 infection of immunocompromised individuals often leads to prolonged
detection of viral RNA and infectious virus in nasal specimens, presumably due to the lack of …
detection of viral RNA and infectious virus in nasal specimens, presumably due to the lack of …
varVAMP: automated pan-specific primer design for tiled full genome sequencing and qPCR of highly diverse viral pathogens.
J Fuchs, J Kleine, M Schemmerer, J Kreibich, W Maier… - bioRxiv, 2024 - biorxiv.org
Time-and cost-saving surveillance of viral pathogens is achieved by tiled sequencing in
which a viral genome is amplified in overlapping PCR amplicons and qPCR. However …
which a viral genome is amplified in overlapping PCR amplicons and qPCR. However …
Bioprocessing and the production of antiviral biologics in the prevention and treatment of viral infectious disease
Emerging, re-emerging and zoonotic viral pathogens represent a serious threat to human
health, resulting in morbidity, mortality and potentially economic instability at a global scale …
health, resulting in morbidity, mortality and potentially economic instability at a global scale …