The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …

Type 1 Diabetes (T1D) is a chronic autoimmune disease characterized by a gradual
destruction of insulin-producing β-cells in the endocrine pancreas due to innate and specific …

Several studies indicate a relationship between maternal gut microbiota alteration and
increased risk of autism spectrum disorders (ASD) in offspring. The possibility of …

We report four patients from two families who presented attacks of childhood‐onset episodic
ataxia associated with pathogenic mutations in the FGF14 gene. Attacks were triggered by …

The transcription factor NURR1 regulates the dopamine (DA) signaling pathway and exerts
a critical role in the development of midbrain dopaminergic neurons (mDA). NURR1 …

In mammals, the cerebellum plays an important role in movement control. Cellular research
reveals that the cerebellum involves a variety of sub-cell types, including Golgi, granule …

Objective The goal of this study was to characterize a Swedish family with members affected
by spinocerebellar ataxia 27 (SCA27), a rare autosomal dominant disease caused by …

Understanding the genetic basis of environmental adaptation in natural populations is a
central goal in evolutionary biology. The conditions at high elevation, particularly the low …

Abstract We identified that Fibroblast Growth Factor 14 (FGF14) was preferentially
methylated in colorectal cancer (CRC). In this study, we aimed to investigate the epigenetic …

Abstract Methcathinone (MC) and 3-fluoromethcathinone (3-FMC) are well-known members
of the synthetic cathinone derivatives, the second most abused group of novel psychoactive …