Regulation of innate and adaptive immunity by the female sex hormones oestradiol and progesterone

KW Beagley, CM Gockel - FEMS Immunology & Medical …, 2003 - academic.oup.com
Women mount more vigorous antibody-and cell-mediated immune responses following
either infection or vaccination than men. The incidence of most autoimmune diseases is also …

Recent observations on HIV type-1 infection in the genital tract of men and women

RW Coombs, PS Reichelderfer, AL Landay - Aids, 2003 - journals.lww.com
The ultimate success of strategies to prevent sexual transmission of HIV depends, in part, on
a better understanding of the virological and immunological mechanisms that define sexual …

Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in …

PWHI Parren, PA Marx, AJ Hessell, A Luckay… - Journal of …, 2001 - Am Soc Microbiol
ABSTRACT A major unknown in human immunodeficiency virus (HIV-1) vaccine design is
the efficacy of antibodies in preventing mucosal transmission of R5 viruses. These viruses …

[HTML][HTML] Enhancing oral vaccine potency by targeting intestinal M cells

A Azizi, A Kumar, F Diaz-Mitoma, J Mestecky - PLoS pathogens, 2010 - journals.plos.org
The immune system in the gastrointestinal tract plays a crucial role in the control of infection,
as it constitutes the first line of defense against mucosal pathogens. The attractive features of …

Differential induction of mucosal and systemic antibody responses in women after nasal, rectal, or vaginal immunization: influence of the menstrual cycle

PA Kozlowski, SB Williams, RM Lynch… - The Journal of …, 2002 - journals.aai.org
A cholera vaccine containing killed vibrios and cholera toxin B subunit (CTB) was used to
compare mucosal immunization routes for induction of systemic and mucosal Ab. Four …

Intranasal immunization with CpG oligodeoxynucleotides as an adjuvant dramatically increases IgA and protection against herpes simplex virus-2 in the genital tract

WS Gallichan, RN Woolstencroft… - The Journal of …, 2001 - journals.aai.org
Abstract Development of vaccines capable of preventing the transmission or limiting the
severity of sexually transmitted viruses, such as HSV and HIV, will likely be dependent on …

Sex steroid hormones, hormonal contraception, and the immunobiology of human immunodeficiency virus-1 infection

Z Hel, E Stringer, J Mestecky - Endocrine reviews, 2010 - academic.oup.com
Worldwide, an increasing number of women use oral or injectable hormonal contraceptives.
However, inadequate information is available to aid women and health care professionals in …

Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody

M Asokan, J Dias, C Liu, A Maximova… - Proceedings of the …, 2020 - National Acad Sciences
Treatment of HIV infection with either antiretroviral (ARV) therapy or neutralizing monoclonal
antibodies (NAbs) leads to a reduction in HIV plasma virus. Both ARVs and NAbs prevent …

Impact of estrogen and progesterone on immune cells and host–pathogen interactions in the lower female reproductive tract

MK Collins, CR McCutcheon… - The Journal of …, 2022 - journals.aai.org
Microbial infections are a threat to women's reproductive health. Although reproductive
cycles and pregnancy are controlled by sex hormones, the impact of hormones on host …

Increased prevalence of sexually transmitted viral infections in women: the role of female sex hormones in regulating susceptibility and immune responses

C Kaushic, KL Roth, V Anipindi, F Xiu - Journal of reproductive immunology, 2011 - Elsevier
Sexually transmitted infections (STIs) caused by viruses, including HSV-2, HIV-1, HPV, are
among the most prevalent infectious diseases worldwide and a major cause of morbidity …