Cumulative multiple early life hits-a potent threat leading to neurological disorders

T Sarkar, N Patro, IK Patro - Brain Research Bulletin, 2019 - Elsevier
Early life Stress is a worldwide concern linked with development of later life neurological
disorders. Early developmental age is sensitive to many prominent environmental insults …

Atypical fetal development: Fetal alcohol syndrome, nutritional deprivation, teratogens, and risk for neurodevelopmental disorders and psychopathology

MK Georgieff, PV Tran, ES Carlson - Development and …, 2018 - cambridge.org
Accumulating evidence indicates that the fetal environment plays an important role in brain
development and sets the brain on a trajectory across the life span. An abnormal fetal …

[HTML][HTML] Toxicity assessment due to prenatal and lactational exposure to lead, cadmium and mercury mixtures

F Zhou, G Yin, Y Gao, D Liu, J Xie, L Ouyang… - Environment …, 2019 - Elsevier
The heavy metals lead (Pb), cadmium (Cd) and mercury (Hg) are common environmental
pollutants that can be detected simultaneously in blood, serum, and urine samples from the …

Hydrogen sulfide alleviates anxiety, motor, and cognitive dysfunctions in rats with maternal hyperhomocysteinemia via mitigation of oxidative stress

O Yakovleva, K Bogatova, R Mukhtarova, A Yakovlev… - Biomolecules, 2020 - mdpi.com
Hydrogen sulfide (H2S) is endogenously produced from sulfur containing amino acids,
including homocysteine and exerts neuroprotective effects. An increase of homocysteine …

Milk fat globule membrane supplementation in formula-fed rat pups improves reflex development and may alter brain lipid composition

S Moukarzel, RA Dyer, C Garcia, AM Wiedeman… - Scientific reports, 2018 - nature.com
Human milk contains nutritional, immunoprotective and developmental components that
support optimal infant growth and development. The milk fat globule membrane (MFGM) is …

Maternal protein malnutrition: Current and future perspectives of spirulina supplementation in neuroprotection

S Sinha, N Patro, IK Patro - Frontiers in Neuroscience, 2018 - frontiersin.org
Malnutrition has been widely recognized as a grave burden restricting the progress of
underdeveloped and developing countries. Maternal, neonatal and postnatal nutritional …

Perinatal inflammation and adult psychopathology: From preclinical models to humans

AM Depino - Seminars in Cell & Developmental Biology, 2018 - Elsevier
Perinatal environment plays a crucial role in brain development and determines its function
through life. Epidemiological studies and clinical reports link perinatal exposure to infection …

Amelioration of neurobehavioral and cognitive abilities of F1 progeny following dietary supplementation with Spirulina to protein malnourished mothers

S Sinha, N Patro, IK Patro - Brain, behavior, and immunity, 2020 - Elsevier
Early life adversities (stress, infection and mal/undernutrition) can affect neurocognitive,
hippocampal and immunological functioning of the brain throughout life. Substantial …

Effects of Melatonin on Neurobehavior and Cognition in a Cerebral Palsy Model of plppr5−/− Mice

Y Sun, L Ma, M Jin, Y Zheng, D Wang… - Frontiers in …, 2021 - frontiersin.org
Cerebral palsy (CP), a group of clinical syndromes caused by non-progressive brain
damage in the developing fetus or infant, is one of the most common causes of lifelong …

Periconceptional folic acid supplementation benefit to development of early sensory-motor function through increase DNA methylation in rat offspring

W Li, Z Li, S Li, X Wang, JX Wilson, G Huang - Nutrients, 2018 - mdpi.com
Periconceptional maternal folate levels may alter DNA methylation patterns and health
outcomes in offspring. We hypothesized that maternal folic acid supplementation alters fetal …