MYCN is a member of the MYC family of proto-oncogenes. It encodes a transcription factor,
MYCN, involved in the control of fundamental processes during embryonal development …

Neuroblastoma (NB) is an aggressive pediatric cancer that originates from neural crest
tissues of the sympathetic nervous system. NB is highly heterogeneous both from a clinical …

Long non-coding RNA (lncRNA) maternally expressed gene 3 (MEG3) has been
demonstrated as an important regulator in diverse human cancers. However, its function and …

Renal ischemia-reperfusion is a main cause of acute kidney injury (AKI), which is associated
with high mortality. Here we show that extracellular vesicles (EVs) secreted from hiPSC …

Simple Summary Neuroblastoma is the second most common solid tumor in children. Our
understanding of the contribution of genetic factors (seed) that contribute to neuroblastoma …

TNF-α is a central proinflammatory cytokine contributing to malignant tumor progression in
tumor microenvironment. In this study, we found the upregulation of miR-105 in colorectal …

Neuroblastoma is a childhood cancer derived from cells of neural crest origin. The hallmarks
of its enigmatic character include its propensity for spontaneous regression under some …

Neuroblastoma (NB), a childhood cancer arising from the neural crest, poses significant
clinical challenges, particularly in cases featuring amplification of the MYCN oncogene …

Neuroblastoma is a neural crest-derived childhood tumor of the peripheral nervous system
in which MycN amplification is a hallmark of poor prognosis. Here we show that MycN is …

Background Neuroblastoma (NB) is a common childhood malignant tumor of neural crest
(NC) origin with remarkable heterogeneity in outcomes. Amplification of the oncogene …